Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"IBD risk loci"”.
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Combining population-scale single-cell transcriptomics with germline genetics to understand the biology of inflammatory bowel diseases
Inflammatory bowel diseases (IBD) are chronic, incurable diseases of the gastrointestinal tract with a high prevalence in the United Kingdom and a growing incidence worldwide. The two most common forms of IBD are Crohn’s disease (CD) and ulcerative colitis (UC). Genome-wide association studies …
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Using single-cell RNA sequencing to elucidate the biological basis of IBD and response to therapy
Inflammatory bowel disease (IBD) is an umbrella term for disorders involving chronic inflammation of the gastrointestinal tract, with over 6 million cases reported worldwide. 320 IBD risk loci have been identified for this disease, however, the role of many of these risk loci in the pathogenesis of …