Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 17 of 17 for “"IBA-1"”.
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Propagasi akasia (Acacia mangium Willd) dengan pemberian kombinasi ZPT BAP (Benzyl Amino Purin) dan IBA (Indole Butryc Acid) secara in vitro
… beberapa konsentrasi BAP yang dikombinasi IBA terhadap pertumbuhan tunas Akasia (Acacia mangium Willd.) pada media MS Penelitian ini dilaksanakan di Laboratorium Kultur Jaringan Tumbuhan, Jurusan Biologi, Fakultas Sains dan Teknologi, UIN Maulana Malik Ibrahim Malang Pada Bulan Mei-Agustus …
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Experimental and Finite Element Evaluation of Mild Traumatic Brain Injury
… tasks, along with histological markers (GFAP, Iba-1, and tau protein), demonstrated that multiple blast exposures resulted in more severe motor deficits and neuroinflammatory responses than single exposures. This highlights cumulative injury risks. To address repetitive rmTBI as observed in …
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A novel approach to the clinical diagnosis and treatment of canine histiocytic sarcoma
… tissues, the study was continued with CD204 and Iba-1 compared to CD18 which is what is currently being used by most pathologists. The IHC stains were performed on 20 tissue samples from dogs previously diagnosed with HS and other soft tissue sarcomas. The results showed that there was only a …
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Il Δ9-THC, componente principale della cannabis sativa, attenua la neurotossicità indotta dalla meth
… ii) ionized calcium binding adapter molecule 1 (IBA-1), marker of microglial activation; iii) brain derived neurotrophic factor (BDNF) and iiii) CB2 receptor. Post-treatment with Δ9-THC 1mg/Kg increase the METH-induced down-regulation of TH and counteract the IBA-1 over-expression induced by …
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Impact of Prenatal Alcohol Exposure on Cognition and Inflammation in Aging Male and Female Rats: A Longitudinal Approach
… recognition memory, serum cytokine levels and Iba-1 cell expression in the dentate gyrus (DG) were assessed at two different time points in the same animals: 6 months (6M) and 12 months (12M) of age. Key findings indicated that PAE leads to cognitive domain-specific impairments, with more …
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Modulation of Alzheimer’s Disease Pathology by Collagen-Induced Rheumatoid Arthritis in APP/PS1 Mice
… with increased blood brain barrier disruption, Iba-1 or Mac-1 positive microglia, and CD45-positive microglia/macrophages. In contrast, CIA reduced survival and vessel density and length with features of cerebrovascular pathology including vascular segments, thinner vessels, and atrophic string …
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ANALYSIS OF ADULT NEUROGENESIS AND HIPPOCAMPUS-DEPENDENT MEMORY IN MOUSE MODELS FOR AGING, ALZHEIMER’S DISEASE AND CRANIAL IRRADIATION-INDUCED NEUROINFLAMMATION
… In the same model we observed attenuation of Iba-1 expressing microglia in the dorsal hippocampus which has been shown to protect cognition. Lastly, RSG was able to reverse Morris water maze spatial learning and long-term memory but not object recognition or context fear discrimination …
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Therapeutic potential of targeting group III metabotropic glutamate receptors as a disease modifying strategy in the treatment of Parkinson’s disease
… to a significant reduction in levels of GFAP and IBA-1 suggesting an additional anti-inflammatory action. Further studies revealed little evidence for co-localisation of mGlu4 receptors with GFAP in the SN <br/>suggesting this anti-inflammatory component likely reflects an indirect effect via …
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Converging Pathways: Neuroimmunology of Tauopathy and Mild Traumatic Brain Injury
… Complex of Guam, showed direct engagement of Iba-1+ microglia by clusters of CD8+ T cells. Interestingly, ablating CD8+ T cells resulted in greater phosphorylated tau deposition, accelerated disease progression, and an increase of all ‘sick’ microglia subsets including a previously …
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APPLICATION OF COMPLEMENTARY METHODS BEYOND STANDARD PATHOLOGY TO INVESTIGATE KETAMINE NEUROTOXICITY IN MODELS OF PEDIATRIC ANESTHESIA
… markers (H&E, Cleaved Caspase-3, γH2AX, GFAP, Iba-1, Olig2, NeuN). A preliminary study compared whole-area analysis with standardized microscopic field sampling, demonstrating that 12 fields per region provided quantitative results comparable to whole-area assessment. A subsequent …
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Diverse roles of cyclooxygenase in the central nervous system and the periphery
… ionized calcium binding adaptor molecule 1 (Iba-1)-positive cells in the periphery infiltrated the core by day five. LIUS markedly reduced CFA-induced inflammatory cells infiltration. These data suggest COX-2 was closely related with edema and immune cell infiltration by pro-inflammatory …
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Neuroprotective effect of mesenchymal stem cells in neurodegenerative disease : focusing on Parkinsonian disease
… hMSC treatment significantly decreased Iba-1, GFAP and increased Calbindine immunoreactive cells in the substantia nigra and the striatum. Behavioral analysis showed that the decent times on the top of a vertical wooden pole was significantly decreased in hMSCs-treated double lesion …
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THE ROLE OF P2X7R IN METHAMPHETAMINE-INDUCED BEHAVIORAL CHANGES AND MICROGLIAL EFFECTOR FUNCTIONS
… concurrent increases in P2X7R expression with Iba-1, a marker of microglial activation after chronic METH treatment in vivo. I confirmed the METH-induced increases in P2X7R protein and mRNA expression in the Embryonic Stem cell derived microglia (ESdM) cell line. siRNA knockdown of P2X7R in …
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CNS Neural/Glial Progenitors as Targets of HIV-1 and Opiates: Effects on Proliferation and Population Dynamics May Alter Behavior Outcomes.
… greater microglial activation (3-nitrotyrosine+/Iba-1+). Unbiased stereological estimation in Nissl staining revealed that the depletion of NeuN immunoreactivity in these mice was not due to neuron cell death or loss, because the total neuron number in striatum and total striatal volume were not …
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Axonal Damage in Repetitive Concussive Traumatic Brain Injury: Characterization and Contributing Factors
… (miRNA-124)--were able to reduce the number of iba-1-positive microglia present in the corpus callosum after injury, which were quantified by stereology. Silver staining was unaffected. Use of the targeted toxin, Mac-1-Saporin, was found to dramatically reduce microglial number but also result …
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Quantifizierung und zelluläre Lokalisation von Eisen in der Substantia nigra bei Patienten mit Parkinsonscher Erkrankung und gesunden Kontrollen
… zellspezifischer Marker (anti-HuC/D, -IBA-1, -GFAP, -CNPase, -OLig2, -MBP, -Ferritin, -HLA) nach Standardprotokoll mit einer Ni-DAB Verstärkung. Histochemische Färbungen nach Perls und Turnbull wurden zum semiquantitativen Eisennachweis durchgeführt. Als Methode zur ortsaufgelösten …
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Risk-Factor Induced Changes In The Breast Microenvironment Facilitate Inflammatory Breast Cancer Progression and Lymphovascular Invasion
<p>Inflammatory breast cancer (IBC) is a rapidly progressing, rare and highly lethal form of breast cancer. IBC is a clinical diagnosis, requiring >1/3 involvement on the affected breast and/or skin by erythema, and disease onset of < 6 months. The clinical symptoms of IBC vary in severity and …