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Showing 1 to 1 of 1 for “"I-BmoI"”.
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DNA hydrolysis and genome editing applications of GIY-YIG family homing endonucleases
… Using the GIY-YIG homing endonuclease I-BmoI as a model system, I investigate the amino acid, nucleotide, and divalent metal ion requirements of the GIY-YIG nuclease domain to generate a double-strand break. I specifically test models of hydrolysis by which enzymes with a single active …