Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"I kappa B kinase"”.
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Role of I Kappa B Kinase Alpha and I Kappa B Kinase Beta in the Development and Function of B and T Lymphocytes
… Activation of NF-κB is regulated by the IκB kinase complex that phosphorylates IκB proteins, leading to their polyubiquitination and degradation. The released NF-κB molecules translocate into the nucleus and activate gene transcription. IκB kinase complex contains two catalytic subunits, IκB …
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EVALUATION OF YAK-KONG SOYBEAN (GLYCINE MAX) FOR ITS PHENOLICS AND METABOLITES WITH A FOCUS ON ATHEROSCLEROSIS PREVENTION
… of VCAM-1, MCP-1 and phosphorylation of I Kappa B Kinase (IKK) in NF-B signaling pathway. In sum, YK has promising potential for further development as a functional food source targeted at atherosclerosis prevention.
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Interrogating novel functions of the I kappa B kinases via CRISPR-Cas9 gene editing and small molecule inhibition
… responses to inflammatory cytokines. The IκB kinase (IKK) complex, which is composed of two catalytic subunits (IKKα and IKKβ) and one regulatory subunit (IKKγ/NEMO) acts as the master regulator of NF-κB transcription factor activity. Seminal genetic studies in knockout (KO) mouse embryonic …