Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 35 for “"Hypothesis generation"”.
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Problem Definition and Hypothesis Generation by Recent Family Nurse Practitioner Graduates
… known about the effect of problem definition on hypothesis-generation accuracy in recent family nurse practitioner (FNP) graduates. The hypotheticodeductive-reasoning model served as the theoretical framework for the study. An alternating-treatment single-subject experimental design was used to …
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Expertise in problem identification: a descriptive analysis of the cue selection and hypothesis generation of reading diagnosticians
… consistency in cue selection and hypothesis generation. Further, their prescriptions appear to be unrelated to their diagnoses. A close examination of this research indicates use of a treatment which restricted the cues which naturally occur in the typical diagnostic process. ln …
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Integrative Approaches in Colorectal Cancer: Prognostic Biomarkers and AI-Driven Hypothesis Generation for Early Diagnosis and Drug Resistance
… ChatGPT provided experimental designs for each hypothesis, but human evaluators found that AI-generated hypotheses often lacked consideration of key biological constraints and feasibility challenges, reinforcing the necessity of human validation. Together, these studies highlight the importance …
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The effects of computer-mediated communication on inductive learning by groups
… process consisting of several rounds of hypothesis generation and testing. In half of the groups, members communicated with each other in face-to-face discussions. In the other half, groups members were physically isolated from each other and communicated through a network of personal …
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A parallel hypothesis method of autonomous underwater vehicle navigation
This research presents a parallel hypothesis method for autonomous underwater vehicle navigation that enables a vehicle to expand the operating envelope of existing long baseline acoustic navigation systems by incorporating information that is not normally used. The parallel hypothesis method …
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B Cell Signaling and Bioinformatics: Revealing Components of the MHC Class II Antigen Processing and Presentation Pathway
… for both of these data sets and facilitates hypothesis generation as to the biological process affected by a specific ligand. As CLASSIFI is strictly a statistical tool that aids in hypothesis generation, experimental validation of hypotheses was performed. The B cell single ligand screen …
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A systems biology approach to understanding and improving butanol production in clostridium beijerinckii
… mechanisms of microbial butanol production; (2) hypothesis generation using model iCM925 for alternative acetate production mechanisms in mutant strain pta::int(17); (3) model-guided knockout candidates for improved butanol production; (4) the first time-series metabolomics study for C. …
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The Associations Between Cardiovascular Disease Risk Factors and Cognitive Function
… (CLSA), and employs machine learning (ML) for hypothesis generation and examining the most significant contributors to cognitive function and impairment in the CLSA. Our review found managing diabetes and hypertension improves cognitive outcomes, while therapeutic control remains inconclusive. …
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A dynamic visual analytics framework for complex temporal environments
… case studies, namely, a case study involving a hypothesis generation scenario, and a second case study involving a cohort-based hypothesis testing scenario. Two evaluations were conducted for each case study involving expert participants. This framework is demonstrated in a neonatal intensive …
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Correlation-based Linking of Epigenomic Regions to Target Genes in Bulk and Single Cell Epigenomic Data
… a significant shift in biological modeling and hypothesis generation. In this study, we present advanced algorithms that utilize multiple modalities for peak-gene linking via correlation-based mechanisms. This approach provides a robust framework for bias correction and noise reduction at …
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The neural correlates of social and non-social decision-making in resolving complex, dynamic uncertainty
… examining the structure and variability of hypothesis generation across individuals. The third study manipulated appraisals directly, instructing participants to assess the informativeness of scenes in relation to a guilt hypothesis. Integrating these findings, the dissertation demonstrates …
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A Reengineering Approach to Reconciling Requirements and Implementation for Context - Aware Web Services Systems
… This approach consists of three stages: 1) Hypothesis generation, where a list of hypothesis source code information is generated; 2) Segmentation, where the hypothesis list is grouped into segments; 3) Concept binding, where the segments turn into a list of concept bindings linking regions …
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VisuaLyzer : an approach for rapid visualization and analysis of epidemiological data
… analysis of up to ten variables. 4. Intelligent Hypothesis Generation: Using computer-identified correlations, together with human intuition gathered through human interaction with visualizations, to intelligently and automatically generate hypotheses about data. VisuaLyzer's power to …
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Models of the Mucosal Inflammatory and Regulatory Immune Pathways: The Role of Host Response in Microbial Persistence and Pathogenesis
… method requires the creation of a unifying hypothesis that reconciles an observed health outcome of infection with experimental data gathered about the disease process following infection. In this era of unprecedented amounts of data and information for various disease models, the creation …
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"It's all just a bit of a mess when drugs are involved, it really is". A narrative study of young people who have recently been discharged from a specialist support service for their substance use
… is hoped that this may lead to better informed hypothesis generation when encountering young people who have problematic relationships with drugs and/or alcohol.
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Polymorphisms in the Flt1 gene and their relation to expression of the secreted Flt1 variant
… in sFlt1 mRNA formation. Here, we test the hypothesis that polymorphisms in the human Flt1 gene, particularly SNPs at sites suspected to contain splicing or cleavage-polyadenylation signals, influence Flt1 pre-mRNA processing and rates of Flt1 and sFlt1 expression. The NCBI SNP database …
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Development of constrained fuzzy logic for modeling biological regulatory networks and predicting contextual therapeutic effects
… methodology to assist data interpretation and hypothesis generation for choice of therapeutic targets.
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VANESA - A bioinformatics software application for the modeling, visualization, analysis, and simulation of biological networks in systems biology applications
… in the Petri net environment of VANESA for hypothesis generation and in silico experiments. VANESA can be applied in many different life sciences, such as fundamental biology, theoretical biology, systems biology, biotechnology, and medical research, among others. The software application …
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Hypothesize-and-verify Based Solutions For Place Recognition And Mobile Robot Self-localization In Interior Hallways
… criterion for selecting the best signatures for hypothesis generation and hypothesis verification. The second approach allows the robot to carry out place recognition and self-localization in constant time. We provide extensive experimental evidence to demonstrate the usefulness of both these …
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Concept graphs: Applications to biomedical text categorization and concept extraction
… applications such as drug discovery, hypothesis generation, and the analysis of molecular structures in chemoinformatics.
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