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Showing 1 to 6 of 6 for “"Hypersensitivity pneumonitis"”.
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HP Turns 17: T helper 17 cell response during hypersensitivity pneumonitis (HP) and factors controlling it
<p>Hypersensitivity Pneumonitis (HP) is an interstitial lung disease caused by repeated inhalation of a wide range of environmental antigens. It is characterized by alveolitis, granuloma formation, and fibrosis. Since HP is a T cell-mediated disease, it is important to determine the type of T cell …
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Protein Kinase D1 in Myeloid Cells Promotes Disease Progression and Severity in S. rectivirgula Induced Hypersensitivity Pneumonitis
Introduction: Hypersensitivity pneumonitis (HP) is an inflammation driven interstitial lung disease characterized by inflammation of the interstitium, bronchioles, and alveoli of the lung that leads to granuloma formation. Myeloid lineage immune cells play a critical role in the early and late …
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Toll-like Receptors 2 and 9 Are Important for Innate Immune Cell Activation and Recruitment in Hypersensitivity Pneumonitis
<p>Hypersensitivity pneumonitis (HP) is an interstitial lung disease caused by repeated inhalation of environmental antigens. The disease is characterized by alveolitis and granuloma formation; however, some patients develop chronic HP (CHP), a restrictive lung disease characterized by fibrosis. …
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The characteristics of intersitial lung disease patients attending Groote Schuur Hospital Respiratory clinic
… & connective tissue disease-ILD (CT-ILD) 26%. Hypersensitivity pneumonitis accounted for 5% of follow-up patients, and only 2 IPF patients were in follow-up. CTD-ILD was the most common diagnosis in new patients: 43% and 29% had sarcoidosis. Five new patients were diagnosed with IPF during the …
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Prognostication and disease monitoring in fibrotic interstitial lung disease
… idiopathic pulmonary fibrosis (IPF) and fibrotic hypersensitivity pneumonitis (fHP), qCT is independently associated with transplant- and progression- free survival. In systemic autoimmune rheumatic disease related ILD, changes in qCT correlated with changes in pulmonary function testing (PFT) and …
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Identification of Therapeutic Targets for Th17 Cell-Mediated Diseases
Hypersensitivity and autoimmune diseases are complex synergistic effect of environmental, genetic and other factors. T helper 17 (Th17) cells play a critical role in the immune pathology. Th17 cells are a group of specialized CD4+ T cells with potential pro-inflammatory function which are different …