Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 6 of 6 for “"Hyperpolarized gas"”.
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Investigation of Deformable Image Registration Based Lung Ventilation Mapping for Radiation Therapy Using a Hybrid Hyperpolarized Gas MRI Technique
… emission tomography scan after inhaling a gaseous radionuclide, as well as hyperpolarized (HP) gas magnetic resonance imaging (MRI) using Helium-3 and Xenon-129 as imaging contrast. Recently, a new method has been proposed in which deformable image registration (DIR) is performed on a pair …
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Fundamental studies and applications for the development of novel MRI contrast agents: Hyperpolarized xenon-129 and superparamagnetic iron oxide nanoparticles
… of two different types of MRI contrast agents: hyperpolarized 129Xe gas and superparamagnetic iron oxide nanoparticles (SPIONs). The largest `Achilles' Heel' of MR techniques is their inherent lack of detection sensitivity due to the exceedingly small magnitude of the nuclear spins, giving rise …
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Eosinophilic Asthma Response to Therapy: 129Xe Magnetic Resonance Imaging and Computed Tomography
… be evaluated using computed tomography (CT) and hyperpolarized noble gas magnetic resonance imaging (MRI), respectively. Computed tomography has previously been utilized to measure airway dimensions, mucus occlusions and pulmonary blood volumes. In contrast, hyperpolarized gas MRI allows for the …
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Clinical-Scale Hyperpolarization of 129Xe and 131Xe via Stopped-Flow Spin Exchange Optical Pumping
… for implementing the large-scale production of hyperpolarized gases that is required for clinical and some specific experimental applications. This research, performed over the past four years, was designed to shed light on some of the practical effects that become critical for scaling up …
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Hyperpolarized Nuclei for NMR Imaging and Spectroscopy – Methodology and model studies of lung and vascular function
… orders of magnitude. The increased signal from hyperpolarized substances enables investigation of non-proton nuclei, and thus makes novel kinds of examinations possible, e.g., imaging of the lungs and respiratory airways after inhalation of hyperpolarized gas. In this work, applications related …
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Quantitative Assessment of Lung Microstructure in Healthy Mice Using an MR-based 3He Lung Morphometry Technique
… this goal we have developed a theory of 3He gas diffusion in lung airways and alveoli and tested this theory in two distinct experiments. In the first experiment, using a Stejskal-Tanner method, we examine the diffusion of 3He atoms as it occurs in tiny airways of mouse lungs. Through a …