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Showing 1 to 3 of 3 for “"Hyperpigmentary disorder"”.

  1. The Effect of Topical Tranexamic Acid Application on Melasma Treatment

    Background and Objectives: Melasma is an acquired hyperpigmentary disorder mainly on the face. Tranexamic acid (TA), a plasmin inhibitor, has been suggested as an efficient treatment modality on melasma. The aim of this study was to investigate the effects and action mechanism of topical TA in the …

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  2. Wnt Modulators, Secreted Frizzled Related Protein (sFRP) 2 and Wnt Inhibitory Factor (WIF)-1, Stimulate Melanogenesis in Normal Human Melanocytes

    … of melanocytes. Previous studies showed that hyperpigmentary skins of melasma express high levels of frizzled-related protein 2 (sFRP2) and Wnt inhibitory factor-1 (WIF-1) compared to perilesional normal skins. In this study, I investigated the functional roles of sFRP2 and WIF-1 on skin …

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  3. The effect of cutaneous vasculature on skin pigmentation

    ABSTARCT i TABLE OF CONTENTS ii LIST OF FIGURES iv LIST OF TABLES vii I. INTRODUCTION 1 II. MATERIALS AND METHODS 3 A. Cell cultures and treatment 3 B. Co-culture using transwell system 4 C. Preparation of the bEnd.3/HUVECs conditioned medium 4 D. Ultraviolet (UV) irradiation of endothelial cells 5 …

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