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Showing 1 to 16 of 16 for “"Hyperkalemia"”.
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Predictors of Hyperkalemia and Outcomes of Dyskalemia in US Veterans with Advanced Chronic Kidney Disease Transitioning to Dialysis
… a dearth of literature on prediction models for hyperkalemia and the effects of dyskalemia on outcomes such as incidence of ischemic stroke and short-term hospital/emergency room (ER) utilization in an advanced CKD population transitioning to dialysis. <strong>Objectives:</strong> Using a …
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Describing the Ionoregulatory Changes that Underlie Cold Acclimation in Drosophila Melanogaster
… a lethal accumulation of K+ in the haemolymph (hyperkalemia). Cold-acclimation can mitigate these ion imbalances, but the physiological mechanisms that facilitate this process are still not understood. Upon adult emergence, D. melanogaster females were subjected to seven days at 25C …
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The Effect of Withdrawal of Angiotensin II Blockers on Serum Creatinine and Potassium in Patients with Chronic Kidney Disease
… renal diseases, but these medications cause hyperkalemia and the elevation of serum creatinine which impede the continuation of the medications. So far, there have been no data which observe the changes of serum creatinine or serum potassium after withdrawal of the RAS blockers. In addition, …
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Regulation of Endocytosis of ROMK Channel by WNK Kinase Family
… disease characterized by hypertension and hyperkalemia. Renal outer medullary potassium channel (ROMK) is responsible for constitutive K+ secretion in the kidney. WNK1 and WNK4 stimulate the clathrin-mediated endocytosis of ROMK, which contributes to the pathogenesis of hyperkalemia in …
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Effects of Perfusate Solution Composition on the Relationship between Cardiac Conduction Velocity and Gap Junction Coupling
… GJ coupling, elevated [Na+]o maintains CV during hyperkalemia. Interestingly, both [Na+]o and [Ca2+]o must be increased to maintain normal CV during hyperkalemia with reduced GJ coupling. These data suggest that optimized fluids can sustain normal conduction under pathophysiologic conditions like …
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Control of the Coqui frog, Eleutherodactylus coqui
… inhibition followed by eventual hyperkalemia.
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With No Lysine 1 (WNK1): A Potential Regulator of The Lysosomal Degradation Pathway
… which is characterized by both hypertension and hyperkalemia. Several groups have used reconstitution assays in Xenopus oocytes and mammalian cell lines to show WNKs regulate the surface expression and/or activity of various ion transporters and channels, including the epithelial sodium channel …
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Clinical characteristics of end stage renal disease patients at hemodialysis initiation
… department (ER group). In the ER group, hyperkalemia and metabolic acidosis were significantly more severe than the OPD group. We hope our study will provide valuable information on the clinical and laboratory characteristics of the patients at the time of hemodialysis initiation in our …
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Investigating the coordination of cardiac conduction and repolarization in ventricular myocardium
… modulate repolarization in the context of hyperkalemia, a common comorbidity of hospitalized patients that increases the risk of arrhythmia. Calcium may potentially play a role in modulating APD adaptation to pacing rate in the context of this disease state, though more research is needed …
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Effects of Perfusate Composition (Na+ and Ca2+) on Cardiac Electrical and Mechanical Function in the Isolated Langendorff-Perfused Heart
… conduction slowing associated with severe hyperkalemia. Likewise, elevating sodium is capable of sustaining intrinsic rhythm where hearts would otherwise go asystolic. In doing so, elevated sodium prevents repolarization prolongation in these hearts. Together, these studies would suggest …
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Sgk1 como mediador de los efectos deletéreos del receptor de mineralocorticoides
… MRAs may produce several adverse effects, like hyperkalemia, sexual dysfunction and hipovolemia. For this reason it would be important, from a therapeutic point of view, to identify genes that simultaneously mediate several of the various negative effects of MR. In this context we studied SGK1, …
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Understanding Potassium Homeostasis Using Human and Mouse Genetic Models
… kinase 1 or 4 (WNK1/4) and featured with hyperkalemia and hypertension. Studies in PHA2 have revealed that WNK kinases regulate renal sodium transporters and potassium channels. WNK1 enhances the endocytosis of renal outer medullary potassium (ROMK) channel through an intersectin-dependent …
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Combination Treatment of Angiotensin-II Receptor Blocker and Angiotensin-Converting-Enzyme Inhibitor in Non-Diabetic Renal Disease on Effect of Reducing Proteinuria
… the amount of proteinuria, the development of hyperkalemia and hypotension in the subgroups. RESULTS: Dry cough was recorded in 10 patients of ACEI group and 4 patients of combination group. Orthostatic hypotension was recorded in 1 patient of ACEI group, 1 patient of ARB group, and 1 patient …
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Effects of pomegranate extract supplementation on cardiovascular disease risk and physical function in patients with chronic renal failure
… its high potassium content may contribute to hyperkalemia-induced cardiac dysfunction. As a result, the efficacy of alternative antioxidant therapies needs to be investigated. PURPOSE: The purpose of this study was to evaluate the effect of 6-month oral supplementation with a pomegranate …
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Nutzen und Risiken der prophylaktischen intraabdominellen Drainage in der elektiven Kolonchirurgie : eine prospektive klinische Beobachtungsstudie
… patients of ndg compared to patients of the dg. (hyperkalemia 3 patients vs. 4 patients, hypokalemia 7 patients vs. 9 patients). Those differences were statistically significant. 15 patients had postoperative complications, the most of these patients had secondary illnesses.Nausea was found in 10 …
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Novel Approaches to the Emergency Management of Hyperkalaemia
Hyperkalaemia is the term used to describe raised potassium level in the blood and, if severe, can constitute a medical emergency. Prevalence estimates have historically varied greatly depending on the population investigated with reports ranging from 1-10% in patients admitted to hospital. …