Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Hypergravitation"”.
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Einfluss von Hypergravitation auf den cGMP-Efflux in Stickstoffmonoxid-stimulierten humanen Melanozyten und Melanomzellen
Gravity alteration is known to affect cell proliferation, morphology, gene expression, and me-tabolism. To our knowledge, studies concerning the gravity influence on melanocyte physiol-ogy with respect to activation and cellular responses that are important for malignant trans-formation have been …
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Differente Expression der Multidrug-Resistenz-Proteine 4/5 in nicht und stark metastasierenden Melanomzellen unter Hypergravitationsbedingungen
Multidrug resistance proteins (MRPs) are transmembrane proteins with the potential to export a wide range of substances in the extracellular space preventing cells from toxification. MRP4 and 5, on which this investigation is focused, particularly mediate nucleoside-analogue export, i.e. guanosine …
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Einfluss der löslichen Guanylylzyklase auf die Expression der cGMP-Exporter MRP4 und 5 in humanen Melanomzellen unter Hypergravitationsbedingungen
Previous studies showed that altered gravity conditions lead to different adaptation responses in various cells, like changes in proliferation, morphology or signal transduction. These changes are forwarded through intracelllular signaling cascades which are, amongst others, mediated by the …