Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 195 for “"Hyperglycemia"”.
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NEW-ONSET HYPERGLYCEMIA AFTER SARS-COV-2 INFECTION
… 2019 (COVID-19) have a higher prevalence of hyperglycemia. By altering glucose homeostasis, cytokine release brought on by The Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection may hasten the onset of metabolic changes. Here, they are described different abnormalities, …
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Genetic Predictors of Hyperglycemia Due to Hydrochlorothiazide Therapy
… with adverse metabolic side effects, such as hyperglycemia, which increase the risk of developing type 2 diabetes. Published approaches testing variation in candidate genes (e.g. the renin-angiotensin-aldosteron system (RAAS) and salt–sensitivity genes) have met with only limited success.</p> …
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Association Between Periodontitis and Hyperglycemia and Metabolic Syndrome Components
… having periodontitis are more likely to have hyperglycemia than those without.</p>
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Perioperative Risk of and Monitoring for Hyperglycemia in Spine Surgery
Perioperative hyperglycemia occurs frequently among patients with and without diabetes and is associated with increased morbidity and mortality. The purpose of this study was to describe perioperative hyperglycemia and to evaluate potential factors associated with postoperative hyperglycemia in a …
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Rgs16 is a Pancreatic Reporter of Chronic Hyperglycemia in Diabetes
… a collection of metabolic diseases with chronic hyperglycemia as their common syndrome. Type 1 diabetes results from pancreatic insulin producing beta cell loss due to autoimmune attack and consequent insulin insufficiency, whereas type 2 diabetes occurs as a result of somatic cell insulin …
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Therapeutic Management of Burn Induced Hyperglycemia with Insulin and Metformin
… pathophysiological changes is the development of hyperglycemia and insulin resistance. These perturbations in metabolism may persist for up to three years following burn injury and are well-established contributors to post burn morbidity and mortality. Accordingly, the implementation of tight …
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Effect of wireless glucose meter on hyperglycemia and prenatal visits
Gestational diabetes mellitus can have devastating effects in the health of the mother and child. While pregnancy rates are decreasing, prevalence of GDM is increasing, and it is estimated that up to 9% of pregnancies are complicated by diabetes in the United States. Traditional treatment and …
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Ceramide Accumulation in the Alpha Cell Drives Glucagon Secretion and Hyperglycemia
… bihormonal-abnormality hypothesis. To perpetuate hyperglycemia in the diabetic state, not only must there be deficient amounts of insulin available, but also excessive amounts of glucagon present. They were the first to provide evidence that hyperglucagonemia in type 2 diabetes mellitus may result …
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Impact of Hyperglycemia on Rat Cortical Bone Microstructure and Osteoprogenitor Cell Exhaustion
… examples of increased proliferation of cells in hyperglycemia from other tissues, we hypothesized that increased osteocyte cell number due to the excessive proliferation of osteoprogenitors increases osteocyte lacunar density in hyperglycemic bone. To address the hypothesis, changes in bone …
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Risk factors for severe intraoperative hyperglycemia in patients undergoing elective neurosurgical surgery
INTRODUCTION: Severe intraoperative hyperglycemia (SIH) is defined as a blood glucose concentration above or equal to 180 mg/dL, and is associated with increased morbidity, including composite infections, leading to increased intensive care unit length of stay, hospital length of stay, and …
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Evaluating Phosphatidylinositide as Lipid Biomarkers for Hyperglycemia-related Triple-negative Breast Cancer Aggressiveness
… conditions. Our findings demonstrate that hyperglycemia enhances aggressive traits in TNBC cells, promoting increased movement and growth, but no effect on ECM attachment. In parallel, lipid profiling revealed alterations in PI molecules that regulate growth and survival pathways, with …
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The Impact of Hyperglycemia on Post-Reperfusion Outcomes in Patients with Hyperacute Ischemic Stroke
… outcomes for ischemic stroke patients. However, hyperglycemia at the time of hospital arrival is associated with worse outcomes, including increased infarct growth, higher rates of disability, and elevated mortality. Despite this, current stroke guidelines neither exclude hyperglycemic patients …
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Hyperinsulinemia and Hyperglycemia Contribute to Diabetic Complications Through Cytokine Resistance and Altered Macrophage Function
… two hallmarks of type 2 DM, hyperinsulinemia and hyperglycemia, and the conditions pertinent to the development of diabetes-accelerated atherosclerosis. Chapters 2 through 4 establish that (1) the rapamycin pathway plays an integral role in serine phosphorylation dependent impaired JAK tyrosine of …
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Role Of Hyperglycemia, Hypoglycemia, and Glucose Transporter 4 on Brain Glucose Sensing, Counterregulation, and Neuronal Viability
… to antecedent hypoglycemia, and: 3) the role of hyperglycemia and the hexosamine biosynthetic pathway: HBP) in the hypothalamus on regulating energy homeostasis. Neuronal GLUT4 was found to play a crucial role in modulating peripheral insulin sensitivity and was necessary for eliciting a full …
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Voluntary wheel running mitigates hyperglycemia-induced depressive-like behavior and increases hippocampal BDNF levels in male mice.
… data suggests this effect is partly mediated by hyperglycemia increasing neuroinflammation and decreasing neurotrophy. While exercise reduces depressive symptoms in other models of depression, limited research has investigated the efficacy of exercise-related interventions in …
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Serum 1, 5 Anhydroglucitol and Glycated Haemoglobin as Markers of Hyperglycemia in Type 2 Diabetes Mellitus at University Teaching Hospital, Lusaka, Zambia
Background: Diagnosis and monitoring of diabetes has long been premised on fasting blood glucose and a hemoglobin-dependent biomarker, glycated hemoglobin A1c (HbA1c), a variant of hemoglobin A. However, adjuncts to these markers, such as 1,5 anhydroglucitol (1,5AG), have since been introduced as …
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AAV9-mediated (Pro)renin Receptor Antagonism Reduces High Fat Diet Induced Hyperglycemia and Hepatic Steatosis in Mouse Model of Non-alcoholic Fatty Liver Disease
… that, AAV9-mediated PRO20 reduces HFD-induced hyperglycemia and hepatic steatosis. A dose dependent study with a higher dose of PRO20 is under way, to better understand the mechanism and outcome of hepatic PRR knockdown in HFD model of NAFLD.
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EFFECTS OF STRESS HYPERGLYCEMIA ACCORDING TO DIABETICSTATUS IN PATIENTS WITH ST-ELEVATION MYOCARDIALINFARCTION AND ITS RELATIONSHIP WITH CARDIAC CELL INJURYAND MITOCHONDRIAL DAMAGE: A TRANSLATIONAL APPROACH
Background: Acute hyperglycemia (AH) is common in ST-elevation myocardial infarction (STEMI) and predicts outcomes. AH is a more powerful prognostic predictor in patients without diabetes mellitus (DM) than with DM, emphasizing the role of an acute glucose rise compared to chronic elevations. …
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Investigating MDM2 Regulation of Endothelial Cell Angiomir Biosynthesis in Response to High Glucose Treatment
… production contributes to the pathogenesis of hyperglycemia-related complications. Although many studies have examined the effect of hyperglycemia on the expression of miRNAs, the effect of hyperglycemia specifically on the endothelial cell miRNA biogenesis machinery is poorly understood. The …
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Characterization of Ocular Surface Pathology and Tear Film Dysfunction Due to Type 1 and Type 2 Diabetes Mellitus
… time demonstrates that, in addition to chronic hyperglycemia, short-duration hyperglycemia causes a rapid-onset ocular surface injury as demonstrated by a decrease in tear film volume, loss of goblet cells, and reduction in corneal glycocalyx. This hyperglycemia-mediated ocular surface injury …
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