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Showing 1 to 7 of 7 for “"Hyperforin"”.
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Supercritical Fluid Extraction Directly Coupled with Reversed Phase Liquid Chromatography for Quantitative Analysis of Analytes in Complex Matrices
… a method for the extraction and analysis of hyperforin in St. John's Wort was developed under air/light free conditions. Hyperforin is a major active constituent in the antidepression herbal medicine-Hypericum Perforatum (St. John's Wort). Hyperforin is very sensitive to oxygen and light. …
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Neurophysiologische Charakterisierung der wasserlöslichen Fraktion eines Johanniskrautextraktes und dessen Einfluß auf die Langzeitpotenzierung
… Zwei der Wirkstoffe, Hypericin und Hyperforin, hielt man bislang für die wesentlichen neuroaktiven Bestandteile von Johanniskrautextrakten. <br>Eine wasserlösliche Fraktion von Hypericum perforatum (HYPWS, hypericum perforatum water soluble), die weder Hypericin noch Hyperforin …
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The premenstrual syndrome: characterisation, diagnosis and treatment
… 900mg SJW/day (0.18% hypericin; 3.38% hyperforin) for two menstrual cycles (n=34). SJW was found to benefit physical and behavioural PMS symptoms, but did not significantly improve mood or pain symptoms. A comparison of various commonly used analytical strategies performed on the data …
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Regulation of P-glycoprotein at the Blood-Brain Barrier
… were exposed to ligands that activate human PXR (hyperforin, paclitaxel), but do not activate rodent PXR. Importantly, an increase in P-glycoprotein expression and transport function was also found in capillaries isolated from rats injected with PCN and dexamethasone (Bauer et al., 2004).
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Development of improved methodologies for the discovery of novel bioactive compounds and their application to problems of biomedical relevance.
… classes of tanshinones, rosmarinic acid, hyperforin and hyguanin C. In all these cases, our simulation results predict that more stable binding of these compounds with enzymes takes place in the active site of the same, so that the compounds would block the entry of the substrate, which …
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Role of transient receptor potential channels in mammalian oviduct and uterine epithelia
… the calcium influx into BOEC. Furthermore, Hyperforin which is a TRPC6 channel activator increased the intracellular calcium concentration in BOEC. TRPC1, 6 and 7 expression in endometrium of patients being treated for infertility by IVF illustrated that gene expression of TRTPC1 and 6 were …