Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 34 for “"Hyperemia"”.
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Coronary Reactive Hyperemia
… The mechanism of post ischemic reactive hyperemia is still unknown but now thought to be multifactorial and perhaps involving purinergic signalling. Purines such as ATP and ADP have recently been discovered to play a vital role in the regulation of vascular tone. We postulated that ADP …
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Adenosine receptors in cutaneous thermal hyperemia and active vasodilation in humans
… receptors in contributing to cutaneous thermal hyperemia. Four cutaneous microdialysis sites were randomly assigned one of four drug treatments designed to elucidate the contribution of A[subscript]1/A[subscript]2 adenosine receptors during local skin heating. Each site was locally heated from a …
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Changes in microvascular hematocrit during post-occlusive reactive hyperemia: descriptions and mechanisms
… (NIRS), during post-occlusive reactive hyperemia (PORH). Mechanisms of reactive hyperemia within skeletal muscle were also explored. The investigation detailed in Chapter 2 of this dissertation found that the differing time courses of the kinetic responses of both oxy- and deoxy[Hb+Mb], …
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Assessing Endothelial Dysfunction Estimating the Differences Between 3 Minute and 5 Minute Reactive Hyperemia
… standard cuff occlusion time to induce reactive hyperemia in assessing endothelial dysfunction. In this study, strong evidence was found by a novel technique that used oscillometric methods, which supported that 3 minute reactive hyperemia was sufficient to elicit a significant difference in …
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Spatiotemporal Dynamics of Tissue Oxygenation in Awake, Behaving Mice
… oxygen supply to respiring cells (‘functional hyperemia’). Recent studies of functional hyperemia in awake rodents shows a bimodal arteriole diameter increase when neural activity is prolonged, indicating at least two primary control mechanisms for an early and late phase. However, it is …
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Influence of Cardiovascular Risk factors on Remote Ischemic Preconditioning
… endothelial vasodilation during reactive hyperemia before and after 65 min of left arm reperfusion injury (20 min brachial artery ischemia followed by 45 min reperfusion) that was preceded by rIPC (right arm: 3X5 min ischemia/reperfusion). All subjects provided written informed consent …
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Retinal Ischemia in the In Vivo Rodent: Cellular and Vascular Characteristics
… and used this technique to study functional hyperemia responses in the retina. We discovered that blood flow increases were more difficult to evoke in areas away from primary arterioles, suggesting that capillary regulation of functional hyperemia is unlikely. To determine the role of glial …
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Modelling Blood Flow & Oxygen Transport in the Active Brain
… increases; this phenomenon is termed functional hyperemia, but it remains incompletely understood. In this thesis, a novel mathematical model of blood flow and oxygen transport in the active brain is developed and used to investigate three aspects of the functional hyperemia response. First, …
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Mechanisms of Blood Flow Restriction Exercise in Skeletal Muscle Adaptations
… as the restriction cuffs are removed, reactive hyperemia occurs, and the increase in nutritive delivery to the muscle is believed to be one of the driving factors that stimulate muscle protein synthesis. Although, mimicking the effect of reactive hyperemia using a pharmacological vasodilator …
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The role of fibroblast growth factor-2 (FGF2) in vascular remodeling and adaptation
… experiments led to the observation that reactive hyperemia was impaired in ischemic limb of Fgf2⁻/⁻ mice. These results indicate that vessel responsiveness is altered in the collateral circulation of the ischemic Fgf2⁻/⁻ limb. This possible identification of FGF2 as a "functional" factor in the …
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Resting Microvascular and Autonomic Function in Relation to Age and Sex Hormone Concentrations
… function was assessed with reactive hyperemia using the microvascular function index (MFI) technique (5mins baseline, circulatory occlusion and reperfusion) and was calculated using the area under the curve of pulse waveforms before and after occlusion/reperfusion. Autonomic function …
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Test Re-Test Reliability of Brachial Artery Flow-Mediated Dilation in Healthy Adults
… condition) and immediately following reactive hyperemia. FMD was calculated as percent change in diameter from baseline. Results: FMD measurements for interday comparisons demonstrated moderate to strong reliability (intraclass correlation coefficient [ICC] = 0.73, P=0.004; CV = 24.7%). …
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Design of a bead holder for thermal atherosclerosis sensor
… reflex of the hand subsequent to induced hyperemia. We created an interface that would securely and reproducibly place the thermal sensor in contact with skin. Our interface (the bead holder) was designed and redesigned until we reached a successful and viable product. The bead holder …
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The Influence of Obstructive Sleep Apnea Syndrome on Insulin Resistance, Metabolic Syndrome, and Endothelial Dysfunction in Young Men
… being assessed from forearm reactive hyperemia after a 5-minute period of upper arm occlusion. Statistics: One-way ANOVA was used to determine group differences in variables. Two-way ANOVA was used to evaluate group x time interactions during the 2-minute recovery period following …
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Relationship Between Intravascular Ultrasound Parameters and Fractional Flow Reserve in Intermediate Coronary Artery Stenosis of Left Anterior Descending Artery
… ischemia was assessed by FFR and maximal hyperemia was induced by continuous intracoronary adenosine infusion. FFR < 0.80 was considered as significant inducible myocardial ischemia. We performed standard IVUS parameter measurements and volumetric analyses. IVUS parameter comparison was …
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Design of a thermal diffusion sensor for noninvasive assessment of skin surface perfusion and endothelial dysfunction
… a phenomenon known as post-occlusive reactive hyperemia (PORH). In my research, I have reviewed the literature regarding endothelial dysfunction and its association with a wide range of cardiovascular risk factors. I have also described the mechanisms thought to link endothelial function in the …
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Peripheral Vascular Function in Young Adults with Increased Risk of Cardiometabolic Disease
… individuals during post-occlusive reactive hyperemia (RHBF), passive limb movement (PLM) and Functional Sympatholysis (FS) trials. Carotid femoral pulse wave velocity (cfPWV) was also collected at baseline, and all values were compared between the Control (Con; negative MetS<sub>index</sub> …
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The Effects of Lowering Cholesterol on Vasodilation
… ultrasound at rest and during reactive hyperemia pre and postintervention. Fifty-three subjects with cholesterol levels above 240 mg/dl were randomly assigned to three groups: Lifestyle change (n=17), medication (n=17), and placebo (n=19).</p> <p>All individuals were assessed for …
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