Global ETD Search
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Showing 1 to 5 of 5 for “"Hydroxyquinolines"”.
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Analogues of Nitrofuran Antibiotics are Potent GroEL/ES Pro-drug Inhibitors with Efficacy against Enterococcus Faecium, Staphylococcus Aureus, and Escherichia Coli
… stronger inhibitors of bacterial growth than the hydroxyquinolines, but were weaker at blocking GroEL/ES functions. However, considering nitrofuran-based antibiotics behave as pro-drugs, it was found that they became much more effective GroEL/ES inhibitors when E. coli NfsB nitroreductase was …
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Homo- and heterodinuclear luminescent helicates
… chelating units were elaborated. Thus, 8-hydroxyquinolines bearing a semicarbazone or SAMP hydrazone group perform in a tetradentate manner; moreover the former tend to agglomeration during complex isolation in the solid state. In contrary, the imine, carboxamide, carboxylate, and imidate …
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Evaluation of F-18 Labeled Hydroxy Quinoline Derivative as a Potential PET Imaging Agent for Early Detection of Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by a progressive cognitive decline in the elderly people older than 65 years of age. The pathological hallmarks of the disease include extracellular senile plaques and intracellular tangles developing during the pre-symptomatic …