Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Hydroxypropylmethylcellulose (HPMC)"”.
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Formulation of novel buccal mucosal drug delivery systems for nicotine replacement therapy (NRT)
Hydroxypropylmethylcellulose (HPMC) and sodium alginate (SA) were used in the formulation of composite wafers and films for potential nicotine (NIC) replacement therapy via the buccal mucosa route. Composite blank (BK), drug loaded (DL) HPMC-SA films (optimized with 2% w/v plasticizer) and wafers …
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Performance and characteristics of controlled release matrices composed of hydroxpropylmethylcellulose and other polymers.
This thesis examines the use of hydroxypropylmethylcellulose (HPMC), sodium carboxymethylcellulose (NaCMC) or ethylcellulose, alone or in combination with other adjuncts, to control the release of propranolol hydrochloride from matrices. Gels were characterized by U tube viscometry and their cloud …
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An investigation into polymeric excipient-drug compatibility in solid-liquid formulations
… investigation were the water-soluble polymers hydroxypropylmethylcellulose (HPMC), hydroxyethylcellulose (HEC), carboxymethylcellulose (CMC), gum arabic (GA), guar gum (GG) and lambda-carrageenan (l-carrageenan). The physico-chemical methods developed in this work help improve the current …
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Drug delivery of paclitaxel for an intraperitoneal chemotherapy
… saline (PBS) supplemented with 0.1% (w/v) hydroxypropylmethylcellulose (HPMC). This formulation showed sufficient physical stability at room temperature and under HIPEC conditions. Initially, both formulations showed similar (<= 10% difference) cytotoxic activity on two cancer cell lines …
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Hydroxypropylmethylcellulose: A New Matrix for Solid-Surface Room-Temperature Phosphorimetry
This thesis reports an investigation of hydroxypropylmethylcellulose (HPMC) as a new solid-surface room-temperature phosphorescence (SSRTP) sample matrix. The high background phosphorescence originating from filter paper substrates can interfere with the detection and quantitation of trace-level …
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DEVELOPMENT OF SUPERSATURATED MATRIX SYSTEMS FOR POORLY WATER-SOLUBLE COMPOUNDS BASED ON SPRAY-DRIED SOLID DISPERSIONS
… hydroxypropyl methylcellulose acetate succinate (HPMCAS) and copovidone S-630, were used in spary-dried dispersion (SDD) formulations. Weak acid drugs glipizide and gliclazide which tend to have limited solubility and dissolution rate were chosen as poorly soluble model compounds representing …
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Development and characterisation of medicated wound dressings for chronic wound healing
… of POL with carrageenan (CAR), chitosan (CS), hydroxypropylmethylcellulose (HPMC) and sodium alginate (SA) in different weight ratios were used to prepare films by the solvent casting technique and evaluated using scanning electron microscopy (SEM), X-ray powder diffraction (XRPD), differential …