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Showing 1 to 18 of 18 for “"Hydroxy acids"”.
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Developing test strips for naked-eye detection of alpha-hydroxy acids using indicator-displacement assays: an application of molecular recognition
… that produce tartrate. Two examples are the dihydroxylation of maleic acid and fumaric acid catalyzed by osmium tetroxide in water, and the hydrolysis of D-dimethyl tartrate. The assay employed a receptor that has 1,3,5-trisubstituted-2,4,6- triethylbenzene scaffold incorporating boronic acid …
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Synthesis of Functionalized Sustainable Polyesters via Controlled Ring-opening Polymerization of O-carboxyanhydrides
… the degradability and biocompatibility of poly(α-hydroxy acids), their utility remains limited because their thermal and mechanical properties are inferior to those of commodity polyolefins, which can be attributed to the lack of side-chain functionality on the polyester backbone. Attempts to …
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A Scrutiny of the Anomalous Behavior of Electrolytically Generated Alkyl Radicals: Part I. The Mechanism of The C(beta)-C(gamma) Cleavage of Gamma-Hydroxy Acids During Kolbe Electrolysis. Part Ii. The Anodic Oxidation of Carbon Radicals to Carbonium Ions
Made available in DSpace on 2014-12-05T19:37:09Z (GMT). No. of bitstreams: 1 5904488.pdf: 5800313 bytes, checksum: aaed9a6be9fbbbf160cf13af32294dc1 (MD5) Previous issue date: 1959
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Part I. Enantioenrichment of α-hydroxy acids through lipase catalyzed esterification; Part II. Synthesis, purification and characterization of novel molecule, sulfonium (3-hydroxy-3-carboxypropyl)-dimethyl chloride; Part III. Synthesis, purification and characterization of potential cancer chemopreventive compound,2-hydroxy-4-(methyl seleno)-butanioc acid
… deals with a preparative scale separation of 2-Hydroxy-4-(methyl thio)-butanoic acid (HMTBA), the hydroxy analog of limiting amino acid Methionine (Met.)...The second section of the dissertation deals with the synthesis of S-methyl HMTBA, an analog of S-methyl methionine (SMM); Vitamin U...The …
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Design of Reagents and Ligands for Direct Palladium-Catalyzed C(sp³)–H Functionalization of Aliphatic Carboxylic Acids
… of C(sp3)–H bonds using carboxylic acids as directing groups. Chapter 2 describes the development of a direct C(sp3)–H fluorination strategy, enabled by the rational design of an oxidizing reagent, marking a conceptual advancement in C–H activation. Building on this concept, Chapter …
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Design and synthesis of novel hydrogels for biological applications
… monomers and their incorporation into poly(2-hydroxyethyl methacrylate) (poly(HEMA)) based hydrogel networks, of interest to the contact lens industry.2) the synthesis of a range of alkyltartronic acids, and their derivatives. These molecules may ultimately be used to produce functionalised …
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Development of systems for isolation of high-valent nickel complexes and their reactivity
… synthesis relies on commercially available alpha-hydroxy acids, and the substituents on the ligand can be varied in a multitude of locations. This ligand synthesis allows for installation of chirality on the methylene backbone of the ligand, which will hopefully result in good chiral projection …
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Nitrophenyl boronic acids as derivatizing agents in chromatography
… of ortho, meta and para nitrophenyl boronic acids were prepared and purified, the purity of these products was examined by GC. The derivatization performance of these acids was studied employing a number of bifunctional model compounds such as: diols, aminoalcohols, hydroxy acids etc. The …
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Some uses of tin compounds in organic synthesis.
… These aldols could be converted to s - hydroxy acids, then treatment with d imethy 1 formamide dimethyl acetal gave allyl stannanes stereospecifically, where steric and reactivity effects allowed. Thirdly, an investigation of the reaction of a tin cuprate with allenes is described. The …
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Novel Pathway Design for Biopolymer Building Block Production
… metabolic pathways to industrially relevant hydroxy acids (HAs) and diols with the ultimate goal of using them for sustainable plastics production. We began by prioritizing bioaccessible HAs for bio-production. Our analysis identified 182 bioaccessible HAs. We prioritized monomers from this …
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A study of lipids from animal skin secretions
… into the investigation of dihydric alcohols and hydroxy-acids and the syntheses of iso-acids which occur in wool wax. Skin secretions which have no commercial applications are nevertheless of great interest from a physiological and biochemical point of view. In this respect human skin secretions …
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Characterization of a Novel Dynamic Combinatorial Depsipeptide System with Implications for the Origin of Biopolymers
… macromolecules whose components, amino acids, are thought to have been present on the ancient Earth—long before biology inhabited the planet. However, the orderly association of these monomers to form functional covalent biopolymers under simulated early Earth conditions has proven …
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Role of Hydroxy acid oxidase 2 (Hao2) in hepatocellular carcinoma
Background: Hydroxy acid oxidases are flavin mononucleotide (FMN)-dependent peroxisomal enzymes. Although it is unclear whether 2-hydroxy acid oxidases contribute to a general mechanism of fatty acid α-oxidation, these enzymes are capable of oxidizing a broad range of 2-hydroxy acids, ranging from …
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3-(R)-Hydroxysäuren als Produkte selektiven Fettsäureabbaus
… werden Studien zur selektiven bakteriellen Hydroxylierung von Fettsäuren vorgestellt. Unter Verwendung von Linolsäure als Substrat wurden aus Bodenproben verschiedene Mikroorganismen isoliert, die polare Metabolite bildeten. Die phänotypische und genotypische Charakterisierung eines Stammes …