Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Hydrogen exchange-Mass spectrometry"”.
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Studies of Protein Stability by Hydrogen Exchange-Mass Spectrometry
… of proteins to reduce long development times. Hydrogen Exchange-Mass Spectrometry (HX-MS) is increasingly being used in pharmaceutical industry for studying protein-protein, protein-ligand, and protein-receptor interactions. However, there is much potential for using HX-MS in a variety of …
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Developability assessments and analytical characterization of recombinant protein antigens formulated as low-cost, multi-dose, aluminum-adjuvanted vaccines
… of biophysical characterization assays and hydrogen exchange mass spectrometry (HX-MS) was used to evaluate the effect of thimerosal on the conformational stability, antibody binding, and backbone flexibility of the parent and a cysteine to serine mutant (C173S) of the NRRV P[4] antigen. The …
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B CELL EPITOPE MAPPING OF RIVAX, A CANDIDATE RICIN VACCINE ANTIGEN
… discontinuous/ conformational epitopes. Based on hydrogen exchange mass spectrometry (HX-MS) studies, VHHS recognized overlapping epitopes with four spatially distinct contact regions i.e. they were grouped into four subclusters (namely 3.1 to 3.4) within cluster III region. Subcluster 3.1 …