Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 8 of 8 for “"Hydrogel particles"”.
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Study of drug delivery and cell encapsulation using biocompatible hydrogel
Hydrogel particles encapsulating biomolecules or living cells are becoming an attractive means to mediate drug delivery or facilitate cell-based treatment of diseases. These particles are capable of maintaining drug stability/cell viability and providing specific drug release profiles. The …
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Extracellular Vesicle Capture and microRNA Detection
… we develop various amplification strategies in hydrogel particles for microRNA detection, including a colorimetric detection platform that can be translated to point-of-care settings for a liquid biopsy. We also explored other amplification strategies for increased miRNA detection sensitivity …
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Advanced flow lithography and barcoded particles
Anisotropic multifunctional particles have drawn much attention, leading to wide ranges of applications from biomedical areas to electronics. Despite their enormous potentials, particles with geometrically and chemically complex patterns are not widely used because existing methodologies have …
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Rational hydrogel design for point-of-care bioassays
… are largely centered on lateral flow assays. Hydrogel microparticles have been used extensively for bioassays due to their nonfouling nature and ability to be functionalized with different types of biomolecules. Here, we use polyethylene glycol hydrogel particles to develop point-of-care …
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Polymer Gels: Kinetics, Dynamics Studies and Their Applications as Biomaterials
The polymer gels especially hydrogels have a very special structure and useful features such as unusual volume phase transition, compatibility with biological systems, and sensitivity to environmental stimuli (temperature, pH value, electric field, light and more), which lead to many potential …
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Immiscible liquid-liquid displacement in microfluidic channels : effects of wettability and geometry
… by incorporating calcium carbonate seed particles into microstructures and growing them with a supersaturated calcium carbonate solution. Using the micromodel fabrication methods thus developed, we have systematically explored oil-water immiscible displacement processes in a controlled …
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Bioorthogonal Functionalization of Elastin-like Polypeptides
… 1) photoreactive ELPs which can generate stable hydrogel particles spanning four orders of magnitude in size; 2) a universal strategy for drug-loaded, targeted ELP nanoparticles by incorporation of a unique site for drug attachment; 3) a sustained-release therapeutic for treatment of brain tumors …
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Engineered 3D microenvironments to understand and direct liver progenitor and cancer cell fate
… TGFβ1 and the introduction of polymer microparticles to push differentiation towards a desired fate. The other system utilized a tunable microarray system to create geometrically controlled hepatocellular carcinoma spheroids and 3D cancer co-culture spheroids with relevant niche cells, …