Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Hydrogel Microparticles"”.
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Synthesis of biodegradable hydrogel microparticles for vaccine protein delivery
Soluble protein antigens used in vaccines have shown lower immune responses when compared with certain particulate forms of these same antigens. For example, it has been shown that micro- and nano-particle mediated delivery of protein antigen can use up to 100 times less protein and still produce …
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Encoded hydrogel microparticles for high-throughput molecular diagnostics and personalized medicine
… This thesis expands the utility of a novel hydrogel-based microparticle array through (1) the creation of a microfluidic, flow-through fluorescence scanner for high-throughput particle analysis, (2) the development of a suite of techniques for the highly sensitive and specific detection of …
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Microfluidic synthesis, characterization, and applications of bioinspired deformable microparticles
Polymeric microparticles have a wide variety of uses, ranging from traditional applications in paints and coatings, to specialized applications in medical therapeutics and diagnostics. For biological applications - including drug delivery, analytical assays, and tissue engineering - it is important …
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Rational hydrogel design for point-of-care bioassays
… are largely centered on lateral flow assays. Hydrogel microparticles have been used extensively for bioassays due to their nonfouling nature and ability to be functionalized with different types of biomolecules. Here, we use polyethylene glycol hydrogel particles to develop point-of-care …
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Manipulating fluids and fields In multimaterial fibers
… as templates to fabricate highly complex 3-D hydrogel microparticles with dielectrophoretic sub-particle localization. Finally, by integrating surface-interfaced porous structures into electrode-integrated fibers, we demonstrate fluid flow manipulation in the radial direction for application …
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Sustainable Hydrogels for Water Treatment
… in low-footprint, resource-efficient processes. Hydrogels (polymer gels containing a significant quantity of bound water) are an ideal platform for the development of new functional materials to bind and degrade micropollutants. Water-based chemistries and a large library of commoditized …
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Engineering Dynamic Granular Composites for the Repair of Cartilage Tissue
… in the stabilization of and control over fusion. Hydrogel microparticles, known as microgels, are being jammed together into granular hydrogels, that are injectable, stabilizing via inter-particle crosslinking, and guiding tissue formation through microporosity and microgel properties. This thesis …
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Microfluidic synthesis and properties of bio-inspired colloids
Today, custom-tailored polymeric hydrogel microparticles are routinely used for drug delivery, medical diagnostics, as well as many fundamental studies in colloidal science. There is growing consensus that physical attributes, such as size, shape, internal structure, and mechanical deformability, …
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Hydrogel-based microfluidic assays for multiplexed medical diagnostics
… from several types of biological fluids. Hydrogels, which are loosely crosslinked networks of polymer chains, are particularly favorable substrates for robust detection of clinical analytes due to their non-fouling properties, ability to immobilize high concentrations of probe molecules, …
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Controlled synthesis of magnetic particles
… addition, we synthesized non-spherical magnetic microparticles with multiple functionalities, shapes and chemistries. Particle synthesis is performed in two steps; polymeric microparticles homogenously functionalized with carboxyl groups were generated AA % using stop-flow lithography, and then …
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Double emulsion droplet microfluidics and high-throughput measurements of single viruses
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-12-01