Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 3 of 3 for “"Hydrofluoroalkane (HFA"”.
-
Polymeric Nanocarriers And Their Oral Inhalation Formulations For The Regional Delivery Of Nucleic Acids To The Lungs
… enhancement in solvation capacity of propellant hydrofluoroalkane (HFA) upon addition of co-solvent ethanol; (ii) the development of efficient HFA-based pMDIs to deliver nucleic acids to the lungs; (iii) the design of siRNA-poly(amidoamine) (PAMAM) dendrimer conjugates. We demonstrate that both …
-
Relative Bio-Equivalence of Salbutamol MDIs Without and With the Attached Spacers. Development and validation of novel HPLC methods for the determination of salbutamol (and terbutaline) in urine excreted post-inhalation for bioequivalence and pharmacokinetic studies of Salbutamol MDIs
This research explored in-vitro and in-vivo performance of three salbutamol metered dose inhalers (MDIs): Ventolin Evohaler (Evo), Airomir (Airo) and Salamol. In the in-vitro studies, critical quality attributes of the MDI using an Andersen cascade impactor (ACI) were examined and included …
-
Performance of two different types of inhalers. Influence of flow and spacer on emitted dose and aerodynamic characterisation.
… operation. In addition, the introduction of the HFAs propellants has led to many changes in the drug formulation characteristics. The purpose of the last section is to examine t h e performance of different types of spacers with different beclomethasone pMDIs. Also, it was to examine the …