Global ETD Search
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Showing 1 to 1 of 1 for “"Huntington's Disease, Neurodegeneration, DNA damage, DNA repair, Transcription, Mitochondria"”.
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Investigation of Huntingtin’s Role in DNA Repair and Transcription
Huntington’s disease (HD) is a devastating and fatal neurodegenerative disease, caused by the expansion of a CAG repeat tract in the mutant Huntingtin gene (mHTT). The mechanism of toxicity imparted by mHTT has yet to be fully elucidated, despite decades of research since its description. Research …