Global ETD Search
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Showing 1 to 2 of 2 for “"Humoral autoimmunity"”.
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Plasmacytoid Dendritic Cell-Mediated Humoral Autoimmunity
<p>Humoral autoimmunity is characterized by the breakdown of B cell immune tolerance to self-antigens and consequent production of pathogenic autoantibodies. Plasmacytoid dendritic cells (pDCs), a potent type I interferon (IFN-I) producer, have been linked to the pathogenesis of systemic lupus …
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Germinal centre autoantibody responses following heart transplantation
The development of humoral autoimmunity following organ transplantation is increasingly recognised, but of uncertain significance. I address the key question whether autoimmunity contributes independently to chronic graft rejection. In a MHC class II-mismatched murine model, I show that antinuclear …