Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 4 of 4 for “"Human trabecular meshwork cells"”.
-
Phenotypic Characterization of Segmental Human Trabecular Meshwork Cells
… Aqueous humor outflow is segmental in the trabecular meshwork (TM) with regions of high-flow (HF) or low-flow (LF) that vary in molecular signature, biomechanics, and response to pressure in both normal and glaucoma eyes. We sought to investigate whether cells in these regions (1) deposit …
-
Determining Mechanisms by which Pathological Extracellular Matrix induces Ocular Hypertensive Phenotypes in Human Trabecular Meshwork Cells
… in several sight-threatening diseases; in the trabecular meshwork (TM), it is implicated in elevated intraocular pressure (IOP), the only treatable risk factor for glaucoma. Herein, two different glaucoma-relevant cell-derived matrices (CDMs) were used to dissect the specific mechanisms by …
-
Drug delivery strategies to overcome ocular hypertension
… these IDNPs was tested in a fibrotic model with human trabecular meshwork cells, where they effectively reduced connective tissue growth factor expression—a marker of fibrosis. These strategies provide enhanced drug delivery through prolonged release or co-delivery, offering promising …
-
Identification of Actin Binding Proteins Associated with Cross-Linked Actin Networks
… with cross-linked actin network (CLANs). Human trabecular meshwork ™ cells were cultured to confluence and treated with dexamethasone or vehicle for 14 days. Total RNA was extracted for gene expression analysis to confirm steroid-induced expression of actin binding proteins in human TM …