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Showing 1 to 1 of 1 for “"Human imunodeficiency virus"”.
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Mutational studies in the dNTP binding pocket of human immunodeficiency virus type 1 reverse transcriptase
It was earlier postulated that Gln 91 of HIV-1 RT stabilizes the side chain of Tyr 183 via hydrogen bonding interaction between 0(H) of Y1 83 and CO of Q91 (Harris et al., BIOCHEMISTRY 37: 9630, 1998). In an attempt to understand the function of Gln 91 in the catalytic mechanism, mutants of this …