Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 103 for “"Human colon"”.
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Diffuse reflectance spectroscopy of human colon tissue
… spectra were collected from adenomatous colon polyps (cancer precursors) and normal colonic tissue of patients undergoing colonoscopy. To analyze the data, an analytical model was developed based on the diffusion of light in tissue. The model was formulated in terms of the absorption and …
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Effect of Soyasaponin Fractions on Human Colon Cancer Cells
… B, as anticarcinogenic agents on the human colon adenocarcinoma cell line Caco-2. Experiments were conducted to determine the effects of purified soyasaponins on cell proliferation, Protein Kinase C (PKC) activity, and cell morphology in cultures of Caco-2 cells. Treatment of cells …
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Polygalacturonate lyase activity in Bacteroides from the human colon
… studies on degradation of dietary fiber by the human colon bacteria, a number of Bacteroides strains from the human colon have been found to degrade polygalacturonic acid and/or pectin. Four of these strains were examined for presence of polygalacturonate lyase (PGAL). The Bacteroides strains …
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PTEN loss induces epithelial-mesenchymal transition in human colon cancer cells
… in tumor invasion. Materials and Methods: Human colon cancer cell lines HCT116 and SW480 were transfected with PTEN siRNA or non-targeting control. Invasiveness was measured using a modified Boyden chamber assay and migration was assessed using a scratch assay. Results. PTEN knockdown …
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Human colon cell migration and socialization induced by small RNA nucleotides
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2024-12-01
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Prevalence and fate of pro-oncogenic clones in the human colon
… of cancer-driver mutations in the normal human colonic epithelium had been so far limited. Using immunohistochemistry and sequencing methods, and by screening a large number of patients and crypts, pro-oncogenic clones were detected for eight colorectal cancer driver genes; ARID1A, APC, …
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An in vitro study of the interactions of bacteria from the human colon.
An in vitro model system inoculated with human faeces was used to study the fermentation of mixtures of bran, cabbage, turnip, carrot and apple dietary fibres. The results suggested that the mixture in which a dietary fibre is supplied influenced its digestibility even though the chemical …
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The Antitumor Agent, Arglabin-DMA, Preferentially Induces Apoptosis in Human Colon Tumor Cells
… tumor growth, the effects of Arglabin-DMA in two human colon tumor cell lines (mutant K-<em>ras</em> HCT 116 and wild-type <em>ras</em> HT-29) were explored on cell proliferation, apoptosis, and cell cycle kinetics <em>in vitro</em>. In cell viability studies, we showed that Arglabin-DMA had …
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Toward an Understanding of Interindividual Variation in Hydrogenotrophic Microbes in the Human Colon
Chapter 4 describes the diversity of colonic SRB and methanogens in native African (NA), African American (AA) and Caucasian American (CA) healthy subjects. In this study, stool samples from NA, who were consuming a diet low in animal protein, versus AA and CA, with both cohorts consuming a typical …
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Enzymatic degradation of alpha and beta cyclodextrins by bacteroides from the human colon
Thirty Bacteroides strains from the human colon were tested for ability to degrade cyclodextrins (CD). Twenty four strains were able to degrade CD. Cyclodextrinase in two of these strains B. ovatus 3524 and B. distasonis Cl8-7 has been studied. Organisms were grown on a minimal medium containing CD …
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The effect of ageing on the innervation and total collagen content of human colon
… muscle (CM) and taenia coli (TC)) in ageing human colon. Macroscopically normal ascending (AC) and descending (DC) colon was obtained at surgery from cancer patients without diagnosis of diverticular disease or inflammatory bowel disease. Masson’s trichrome and Picrosirius red stains were …
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Regulation of cytotoxic drug-induced apoptosis by death receptor 5 in human colon cancer cells
… drug that is widely used for the treatment of colon cancer. However, 5-FU-resistance is still a common issue which needs to be overcome. Understanding the molecular pathway of 5-FU-induced apoptosis will help designing more effective cancer treatments. Chemotherapeutic drugs such as 5-FU are …
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THE ROLE OF EPIGENETICS IN TRANSCRIPTIONAL REGULATION OF FXR AND SILENCING FXR EXPRESSION IN HUMAN COLON CANCER
… disorders, metabolic syndrome, and liver and colon cancer. Studies suggest epigenetic mechanisms are critical for proper transcriptional induction of nuclear receptors. Likewise, evidence shows epigenetic mechanisms are responsible for modulating the tissue/cell-specific FXR expression in …
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Regulation of tumor necrosis factor-alpha induced apoptosis via posttranslational modifications in a human colon adenocarcinoma cell line
(cont.) phosphoproteomics technology, IMAC/LC/MS/MS, [approximately] 200 phosphosites were identified from HT-29 cells, some of which were detected only from insulin-treated cells. Our phosphoproteomics approach also enabled us to detect alteration of both known and unknown phosphorylation states …
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Antigenic and Ultrastructural Properties of the Plasma Membrane of Cultured Cells Derived From Carcinomas of the Human Colon and Rectum
Made available in DSpace on 2014-12-11T21:33:51Z (GMT). No. of bitstreams: 1 7511861.pdf: 8702552 bytes, checksum: c2df65d7ffb9f2fdae4a2b66b337699f (MD5) Previous issue date: 1974
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The Effects of a Purified B-Group Soyasaponin Fraction on the Proliferation, Cell Cycle Progression and Induction of Macroautophagy in Hct-15 Human Colon Adenocarcinoma Cells
Colon carcinoma is the second largest cause of cancer-related mortality in the United States. Diet has been recognized as an important modifier of colon cancer development for decades. Specifically, dietary patterns that include legumes, such as soybeans, may reduce colon cancer progression. High …
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Genetic characterization of the mucopolysaccharide utilization system of Bacteroides thetaiotaomicron
… for the bacteria that normally reside in the human colon. The finding that some of the major colonic species such as Bacteroides thetaiotaomicron can utilize host-derived polysaccharides as well as dietary polysaccharides raised the question of whether host-derived polysaccharides might be an …
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