Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 127 for “"Human blood"”.
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The rheology of human blood
Thesis (Sc. D.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1963.
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Somatic evolution in human blood and colon
… clone; yet these remain poorly understood in humans. One tissue was selected for the exploration of each of these two facets of somatic evolution: blood for clonal dynamics; colon for mutational processes. Blood presents an opportunity to study normal human clonal dynamics, as clones mix …
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Some physical and rheological properties of human blood.
Thesis: Sc. D., Massachusetts Institute of Technology, Department of Chemical Engineering, 1966
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The viscosity of human blood at high hematocrits
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Chemical Engineering, 1986.
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Enzyme Linked Immunological Studies of Cholinesterases in Human Blood
A modified Ellman method using acetylthiocholine as substrata has been used to reliably measure erythrocyte AChE activity (CV=7%). Reliable immunological quantitation of this enzyme (CV=7%) was achieved using monoclonal antisera to AChE (AE-1 and AE-2) in a fluid phase homogeneous enzyme-linked …
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An empirical constitutive equation for anti-coagulated human blood
A constitutive equation for whole human blood was developed using a power law functional form. This power law equation contains two parameters, the consistency index and the non-Newtonian index for the fluid. Viscometric data, utilizing a cone and plate viscometer, were obtained from anticoagulated …
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CD30: A Novel Receptor to Induce Apoptosis in Human Blood Eosinophils
… the expression and role of CD30 in apoptosis of human blood eosinophils. Percentage of apoptotic eosinophils was determined by Annexin V/PI labeling and CD30 expression was examined by flow cytometry. Spontaneous apoptosis was induced by serum deprivation, and survival was conferred by incubating …
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Impact of human blood plasma-derived protein corona on extracellular vesicle uptake
… When a nanoparticle is introduced into blood plasma, plasma proteins are adsorbed to its surface, forming a protein corona. The formation of the corona is a dynamic process, governed by individual protein concentrations as well as their respective affinities for the surface. Proteins of …
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U0126, MEK1/2 inhibitor, Induces Adhesion Molecules Expression in Human Blood Cells
… molecule by MEK1/2 inhibotors such as U0126 in human blood cells, U937 cells. Cell viability was determined by MTT assay. The expression of adhesion molecule was observed by flow cytometry. Adhesion molecules were time- and dose-dependently incresed by U0126. U0126 decreased ERK activity in a …
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Measurement of glucose in human blood serum using near-infrared Raman spectroscopy
Thesis (M.S.)--Massachusetts Institute of Technology, Dept. of Mechanical Engineering, 1998.
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Mitochondrial function in sepsis - Temporal evolvement of respiratory capacity in human blood cells
… response, including dysfunctional peripheral blood immune cells has been described as part of the septic syndrome. Mitochondrial dysfunction has been suggested to be a contributing factor in the pathogenesis of these alterations and restoration of mitochondrial function has been implicated as …
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Development and application of novel approaches to quantitate therapeutic drugs in human blood
… methods to detect the drug at pg/mL levels in blood. Using an Agilent Zorbax SB-Phenyl column, intra- and inter-assay precision RSD values were found to be less than 15% at the concentrations examined (10-200 pg/mL). The assay LOQ was 10 pg/mL with a linear response up to 200 pg/mL. Successful …
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Chloride Channels in Normal Human Blood Monocytes and a Macrophage-like Cell Line
… In this work, we examined chloride currents in human blood monocytes and macrophages, and their role in adhesion and migration. Chloride currents were recorded in freshly isolated human blood monocytes and WBC264-9C cells (a macrophage-like cell line) using the whole-cell patch clamp technique. …
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Next Generation Sequencing-Based Genotyping of Human Blood Groups: FY, JK and ABO Genes
Serological discrepancies in matching blood group antigens between donors and patients for blood transfusion may lead to alloimmunisation, especially in multiply transfused patients. Blood group genotyping (BGG) has contributed in reducing this issue. ABO, Fy and Jk antigens are among those to be …
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The effect of non-coding variants on gene transcription in human blood cell types
… my PhD I have studied the regulatory effects of human genetic variation. To do so I have processed and analysed datasets measuring effects of genetic variants on transcript levels of genes, identified regulatory variants and put them in bigger biochemical and physiological context. Expression …
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Anti-allergic drug and intracellular signaling mechanisms in human blood eosinophils and airway epithelial cells,
… cytokine production from T cells, suppress blood and tissue eosinophilia, inhibit IgE production, and prevent goblet cell metaplasia, it was my hypothesis that IPD inhibits a pro-inflammatory pathway in human blood eosinophils and airway epithelial cells involving G-proteins and decrease in …
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Generation and Characterization of Human Blood-Brain Barrier Models for Investigating Neuropsychiatric Disorders and Tumor Metastasis
<p>The blood–brain barrier (BBB) is important in the normal function of the central nervous system (CNS). An altered BBB has been described in various neuropsychiatric disorders. The brain-specific microvascular endothelial cell (BMEC) is an essential structural component of the BBB. To test if …
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Non-invasive Measurement of Cholesterol in Human Blood by Impedance Technique: an Investigation by Finite Element Field Modelling
… for determining cholesterol levels in human blood non-invasively by electrical impedance technique. The main part of this research is focused on the development of methodologies for numerical finite element (FE) modelling of simplified blood-cholesterol system, representing a real …
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