Global ETD Search
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Showing 1 to 3 of 3 for “"Human Islet Transplantation"”.
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Gene Therapy and Stem Cell Therapy to Improve the Outcome of Human Islet Transplantation
… introduction in 1990s, the Edmonton Protocol for human islet transplantation has helped more than 500 patients with type 1 diabetes worldwide and met great success from bench to bedside. The Edmonton Protocol involves isolating islets from a cadaveric donor pancreas by enzymatic digestion and …
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Evaluation of a high-yield technique for pancreatic islet isolation from deceased canine donors
… and frequent complications. Pancreatic islet transplantation is a noninvasive and potentially curative treatment for T1DM. We hypothesized that clinically acceptable islet yield and purity could be achieved by using deceased canine donors and standard centrifugation equipment. Pancreata …
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Microencapsulated human islets as a therapy for type 1 diabetes
Microencapsulating human islets is a means being explored to overcome the immune mediated destruction of the graft without toxic immunosuppression. Despite promising studies in various animal models, encapsulated human islet transplantation has so far not made an impact in the clinical setting. …