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Showing 1 to 1 of 1 for “"Human Dose Prediction"”.

  1. Utilization of Model-Based Approaches to Maximize Efficacy of Antibiotics for the Treatment of Mycobacterium abscessus Pulmonary Infection

    … efficacy of drugs against Mab-PI. Lastly, a human physiologically based pharmacokinetic (PBPK) model for inhaled TGC was developed to predict exposure in the systemic circulation and major organs associated with toxicity. Based on clinically and preclinically established adverse event …

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