Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 8 of 8 for “"Human Dermal Microvascular Endothelial Cells"”.
-
Extracellular Vesicles as Mediators of Communication Between Endothelial Cells and Fibroblasts
… coincides with angiogenesis, the mechanisms of endothelial-fibroblast cross-talk remain poorly defined. One emerging mode of intracellular communication is through extracellular vesicles (EVs), capable of transferring regulatory molecules such as microRNAs (miRNAs) to nearby or distant cells. …
-
PEGylated Tissue Repair Peptide TP508 Derivatives as Second Generation Drugs for Radiomitigation and Other Systemic Applications
… represents a specific receptor-binding domain of human thrombin with many potential clinical applications. However, it shares several weaknesses common to peptides when administered systemically, such as a short circulating half-life and rapid proteolytic degradation. One FDA-approved method for …
-
Microvascular endothelial response to cocaethylene exposure: morphological and molecular observations
… that were used to test the hypothesis that the microvascular endothelium is a target tissue that is central in the pathogenic mechanism of cocaine-associated systemic disease, and that endothelial injury after CE exposure would result in dysregulation and altered barrier function due to changes …
-
Design and Optimization of Angiogenic, Antibacterial Si-Zn-Hydroxyapatite for Use as Filler Particles in Polycaprolactone Nanocomposites
… investigation. In vitro co-cultures of human osteoblasts (hOBs) and human dermal microvascular endothelial cells (hDMECs) on dense Si-Zn-HAp surfaces revealed that osteogenic and angiogenic activity are governed primarily by surface properties rather than direct ionic stimulation. Si …
-
Design of a Gel-in-Scaffold Hybrid Substrate for a Multicellular Endometrial Model
… of composition of the gel component. Human dermal fibroblasts (HDFs) were cultured within different substrates to assess their spatial distribution, morphology and interactions with the surrounding matrix. Infiltrating CG into a scaffold (at least 10-XL) significantly reduced the …
-
Effects of Surface Characteristics of Hydroxyapatite and Substituted Hydroxyapatites on Protein Attachment and Angiogenesis
… adhesion in mono- and co-culture using primary human osteoblasts (hOBs) and human dermal microvascular endothelial cells (HDMECs), with- and without FN pre-coating. A hOB:HDMEC cell ratio of 70:30 was found to promote vessel formation on all biomaterials. 1.25wt%Si-HA and Bio-Oss® discs were the …
-
The Influence of Structure and Surface Biochemistry on Cell Function and Angiogenesis in Collagen Scaffolds
… survival including the supply of nutrients to cells and waste exchange. Therefore, in order to prevent core degradation of tissue-engineered grafts, it is important to provide appropriate physico-chemical conditions to encourage angiogenesis in the period immediately following implantation. …
-
An investigation into the molecular mechanisms of hyperbaric oxygen using a human dermal microvascular endothelial cell line and a porcine retinal explant model.
… are a major cause of morbidity and mortality. Endothelial dysfunction is central to microvascular complications such as diabetic retinopathy (DR) and impaired wound healing in diabetes. Hyperbaric oxygen therapy (HBOT) is the administration of hyperbaric oxygen (HBO) which involves breathing ≥ …