Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 7 of 7 for “"Human Coronary artery endothelial"”.
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Mechanisms of HIV-Nef Induced Endothelial Cell Stress: Implications of HIV-Nef Protein Persistence in Aviremic HIV Patients
… cardio-pulmonary vascular pathologies such as coronary artery disease, pulmonary hypertension and emphysema remain a major issue in the HIVinfected population even in the era of antiretroviral therapy (ART). The continued production of HIV encoded pro-apoptotic protein, such as Nef in latently …
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Adverse Childhood Experience-conditioned serum from young adults promotes a dysregulated endothelial cell gene expression profile
… to these outcomes remain poorly understood. Endothelial dysfunction is one of the earliest signs of cardiac pathology and can establish long-term changes in inflammatory state, blood composition, and vasomotor activity. The objective of this study was to investigate gene expression changes in …
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A new insight on direct actions of Granulocyte-Colony Stimulating Factor in the myocardium
… in der Ratte koronares Kollateralwachstum (engl. coronary collateral growth, CCG) stimulieren würde. Einzelne Versuchstiergruppen wurden dafür repetitiven Episoden einer 40 Sekunden andauernden Okklusion des Ramus interventricularis anterior der linken Koronorarterie (engl. left anterior …
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Altering Nitric Oxide Bioavailability and Lipid Profiles in Endothelial Cells By Polycyclic Aromatic Hydrocarbons in Particulate Matter
… (ROS). Lipid peroxidation involves regulating endothelial nitric oxide synthase via inhibition of its activity, and as a result, mediates dilation of coronary arterioles is involved with the pathogenesis of atherosclerosis. However, data on assessment of oxidized lipid formation is limited due …
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Dysregulation of connexin-43 (cx43) in doxorubicin-induced cardiotoxicity
… localisation of connexin-43 (Cx43) in rodent and human cardiac cells and cells of the vasculature to identify if drug treatment impacts this important cardiac connexin. Through investigating the cardiotoxic effects of DOX, this project has shown that total Cx43 protein levels were reduced in human …
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Vascular calcification as a risk factor for peripheral arterial disease and its effects on angiogenesis
… calcium on ischemia-driven angiogenesis. Human coronary artery endothelial cells were cultured and incubated with calcification medium (CM) (CaCl₂ 2.7mM, Na₂PO₄ 2.0mM) for 24h and conditioned to either normoxia or hypoxia. The Hindlimb ischemia model was used to assess the role of high …