Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 14 of 14 for “"Ht1"”.
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Charakterisierung der Serotonin-Rezeptoren der Honigbiene Apis mellifera : von den Genen zum Verhalten
… legten nahe, dass es sich dabei um einen 5-HT1- (Am5-HT1) und zwei 5-HT2-Rezeptoren (Am5-HT2α und Am5-HT2β) handelt. Die strukturelle Analyse der abgeleiteten Aminosäuresequenz dieser Rezeptoren postuliert das Vorhandensein der charakteristischen heptahelikalen Architektur von GPCRs und …
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Klonierung und Charakterisierung aminerger Rezeptoren der Amerikanischen Schabe Periplaneta americana
… die größte Ähnlichkeit zu Mitgliedern der 5-HT1- und 5-HT7-Rezeptorklassen bzw. den Invertebratentyp-Dopaminrezeptoren auf. Die isolierten Rezeptoren der Amerikanischen Schabe wurden dementsprechend Pea(Periplaneta americana)5-HT1, Pea5-HT7 und PeaDop2 benannt. Das Hydropathieprofil dieser …
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Effect of Resistance Type on the Development of and Yield Losses Due to Northern Corn Leaf Blight
… used, one version carrying the resistance gene Ht1 and the second carrying the corresponding allele for susceptibility, ht1. Plots were inoculated at one of five different times, corresponding to growth stages (GS) 2 through 6.
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Promoter Polymorphisms of Cysteinyl Leukotriene Receptor 1 (CysLTR1) Influence the Effect of Leukotriene Modifier on Transcriptional Regulation of the CysLTR1 Gene Induced by IL-4
… male subjects; the common 3 SNP haplotypes, ht1 [C-A-A], was associated with decreased disease risk (p=0.031 for AIA vs. NC; p=0.022 for AIA vs. ATA), and the ht2 [T-C-G] haplotype with increased disease risk (p=0.031 for AIA vs. NC; p=0.031 for AIA vs. ATA). Moreover, 3 SNPs can modulate …
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Molekulare und pharmakologische Charakterisierung von Serotonin-Rezeptoren der Honigbiene Apis mellifera
… von Drosophila melanogaster bzw. dem 5-HT1-Rezeptor von Panulirus interruptus auf. Die isolierten Serotonin-Rezeptoren der Honigbiene wurden dementsprechend Am(Apis mellifera)5-HT1, Am5-HT2 und Am5-HT7 benannt. Das Hydropathieprofil des Am5-HT1-, Am5-HT2- und Am5-HT7-Rezeptors deutet auf …
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Genetic Effect of ALOX15 Polymorphisms on Aspirin-Exacerbated Respiratory Disease
… genotype of -427G>A polymorphism (P = 0.016) and ht1 [GCG] (P<0.001). The promoter activity of ht1 [GC] construct was significantly higher compared to that of ht3 [AG] construct in A549 and U937 cells (P<0.001, respectively). Moreover, -427 G specific binding protein was observed by EMSA. The AERD …
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Genetic association study of interleukin 6 receptor and liver X receptor in systemic lupus erythematosus
… for three polymorphisms were constructed: HT1 [GTA], HT2 [ATC], HT3 [ATA], HT4 [GTC] and HT5 [GAA]. There were no significant differences between SLE and NC. However, the frequency of rash (p=0.037), leukopenia (p=0.033) and lymphopenia (p=0.027) were significantly higher in SLE patients …
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Characterization of 5-Hydroxytryptamine-Evoked Isometric Contractile Responses in Aortic Vascular Smooth Muscle in Thyropathological Rats
… effect may reflect activity of the ligand at 5-HT1 or 5-HT2 receptors differentially sensitized by thyropathology. These data suggest that thyropathological alterations in 5-HT1 or 5-HT2 receptor subtype-mediated responses occur in rat thoracic aorta.
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Molecular genetic mechanisms of eosinophil activation in aspirin-exacerbated respiratory disease : Genetic mechanisms of eosinophil activation
… for two polymorphisms were constructed: HT1 [AT], HT2 [GT] and HT3 [GG]. There was no significant difference between asthmatics and NC. In association of IL5RA polymorphisms, there were no significant differences in the genotype and allele frequencies of the three polymorphisms among the …
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Significant Association of IL-18 Genetic Polymorphisms with Aspirin-Intolerant Urticaria in a Korean Population
… The promoter-reporter construct carrying the HT1 [CG] displayed significantly higher luciferase activity than those with other haplotypes, HT2 [AG] or HT3 [AC] in two different cells including HMC-1 and Beas2B. EMSA finding showed that CREB2 bound more tightly to the -607C allele sequence than …
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On the Binding of N1-substituted Tryptamines at h5-HT6 Receptors
… family which consists of seven classes (5-HT1-5-HT7). 5-HT6 receptors are G-protein coupled, positively coupled to an adenylate cyclase second messenger system and are primarily found in the central nervous system (CNS). The exact functional role of 5-HT6 receptors has not been determined, …
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Genetic Effect of MBL2 Polymorphisms in Patients with Diisocyanate-induced Occupational Asthma
… The DI-OA exposed subjects carrying ht1 [GAG] showed higher serum MBL levels (P=0.004), while the subjects carrying ht3 [CAC] had significantly lower serum MBL levels (P=0.020) than those with others. The luciferase activity was enhanced significantly in the construct containing -554G …
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Evaluation of race population distribution, fungicide sensitivity, and fungicide control of Exserohilum turcicum, the causal agent of northern leaf blight of corn
… screened on corn differential lines containing Ht1, Ht2, Ht3, Htm1, and Htn1 resistance genes. Isolates were collected from fields in Illinois, Indiana, Iowa, Minnesota, North Carolina, Ohio, and Wisconsin, including: 143 isolates collected between 2007 and 2014; and 13 isolates collected …
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Development of 'In vitro' intestinal models to study the pharmacology of drugs affecting the gastrointestinal tract in normal and diseased conditions. Development of a cell culture model for intestinal pharmacology.
… adults. The pre-treatment with methysergide (5-HT1/2/5-7 receptor antagonist), ritanserin (5-HT2 receptor antagonist), granisetron (5-HT3 receptor antagonist) and RS 23597 (5-HT4 receptor antagonist) at 1¿M or a combination of ritanserin, granisetron, plus RS 23597 at 1¿M significantly reduced …