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Showing 1 to 3 of 3 for “"Hot Melt Extrusion (HME) process"”.
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Characterization of Drug-Loaded Milled Extrudate Particles Produced by Hot Melt Extrusion Technology for Dry Powder Inhalers
… inhalation (DPI) formulation through continuous Hot Melt Extrusion (HME) process and see the impact of Sodium Bicarbonate (SB) and Mannitol (MAN) on the hydrophobic Eudragit RL PO (ERLPO) polymer. Ball milling and air-jet milling were utilized to have powder with a particle size range that is …
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Batch foaming of hot melt extruded excipient/disintegrant/API pharmaceutical formulations and the study of the effects of the resulting cellular structures on API dissolution
… In the first part of this research, the Hot Melt Extrusion (HME) process is used to compound the following pharmaceutical formulations: EPO/AcDiSol/INM and EPO/Cros/INM containing different percentages of disintegrant. Comprehensive characterization of this system carried out by Hot-stage …
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Foaming of amorphous drug delivery systems prepared by hot melt mixing and extrusion
… and pharmaceutical industry in exploring foaming processes and their products in drug delivery applications. However, there is still little knowledge of the impact of the morphology of the foamed structures on the performance of drug products in spite of some publications in this area. Therefore, …