Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 8175 for “"Host"”.
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VIRUS-HOST INTERACTIONS AND THE IMPACT ON HOST CELLULAR MECHANISMS
… pandemic potential and exhibit an expansive host range, a characteristic underpinned by their conserved ephrin receptors. Being a highly virulent zoonotic pathogen, NiV has caused recurrent outbreaks in Southeast Asia with mortality rates ranging from 40% to 100% among infected individuals. …
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Mechanism of Host Specificity and Host Range of Nosema Algerae
Made available in DSpace on 2014-12-12T01:27:42Z (GMT). No. of bitstreams: 1 7317659.pdf: 5150663 bytes, checksum: 681920e404ccdc76bc059bfab2ebffd2 (MD5) Previous issue date: 1973
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Host-Microbiota Interactions
… a variety of niche metabolic pathways that the host does not possess. For example, the microbiota produces butyrate, which provides the colon’s epithelial cells with about 70% of their energy needs. The typically fast proliferation of tumor cells in CRC patients drastically alters the tumor’s …
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AY-‐WB phytoplasma manipulations of host and non-‐host leafhopper interactions
Hempitera. In plant hosts, phytoplasmas induce physiological changes and in both hosts modulate plant-‐insect interactions. Previously, interactions have been examined with both hosts infected with phytoplasmas. Thus, it is unclear which organism the effect stems from or how phytoplasmas …
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A cholera model linking between-host, within-host and environmental disease dynamics
… respective time scales. Specifically, the within host system incorporates the interaction of virus and immune cell interaction with the vibrios. For each subgroup, we discuss the existence and uniqueness of a DFE (Disease Free Equilibrium) by calculation of the Basic Reproduction number R_0, when …
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Integrative genomic approaches to dissecting host-tumor and host-pathogen immune processes
Two parallel research efforts were pursued. First, we conducted a systematic exploration of how the genomic landscape of cancer shapes and is shaped by anti-tumor immunity. Using large-scale genomic data sets of solid tissue tumor biopsies, we quantified the cytolytic activity of the local immune …
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Vip And Host Immunity
… dissertation was to examine how VIP regulates host immunity and corneal healing, specifically, its control of growth factors and TLR expression in the P. aeruginosa infected cornea. Firstly, VIP treatment increased growth factor expression (EGF, GHF, FGF and VEGF) in infected cornea. Notably, …
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Host response in sepsis
… peptides, AMPs). Increased knowledge of the host response in sepsis will aid in refining and developing new treatment. We investigated the effect of the AMP, LL-37, on smooth muscle activity in isolated human omental vessels and found that it causes formyl peptide receptor-like 1 mediated …
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Dengue Virus Host Factors
… dengue virus interacts with its insect and human hosts will facilitate the intelligent design of specific antivirals to combat the disease and enable the selective breeding of mosquitoes resistant to the virus. Although the genomes of the two primary mosquito vectors have been sequenced, the …
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SARS-COV-2 EVOLUTION AND TRANSMISSION: WITHIN-HOST, BETWEEN-HOST, AND BETWEEN-SPECIES
… adaptations between vaccinated and unvaccinated hosts, and explore interspecies transmission between humans and animals. We found that SARS-CoV-2 evolution rates are increased during prolonged immunocompromised infection, with dominant drug resistant substitutions arising within weeks of …
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Host Attraction and Host Selection in the Family Corethrellidae (Wood And Borkent) (Diptera)
… wing-beat frequency. For the first time, the hosts of corethrellids were identified to species based on blood meal analysis. Using flies collected over six years at two locations in the SE USA, the host species data were compared to potential host abundance. Host feeding patterns did not …
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Multi-scale Transmission Ecology: How Individual Host Characteristics, Host Population Density, and Community Structure Influence Transmission in a Multi-host Snail Symbiont System
… infectious agents and other symbionts through host populations and communities, we need dynamic mathematical models that accurately portray host-symbiont transmission. But transmission is an inherently difficult process to measure or study, because it is actually a series of interacting …
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Immunomodulatory Effect Of Host And Fungal Eicosanoids During Host-Pathogen Interactions With Candida Albicans
… oxylipins that cross-react functionally with host eicosanoids, which are considered to play important role in regulating innate and adaptive immune responses. Our objective was to characterize the role of prostaglandins produced by the host and this fungus during host pathogen interactions, …
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Analysis of Bacterial-Host Interactions Between Campylobacter jejuni and the Avian Host During Commensalism
… between C. jejuni and the natural avian host was examined to better understand the interactions that contribute to commensalism. We analyzed the colonization dynamics of C. jejuni over 28 days and identified a previously uncharacterized prolonged, robust colonization of the bursa of …
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West Nile virus versus the host cell: Identification of host factors that modulate infection
There are two competing aspects of virus-host interactions: (i) those that enhance virus transmission and (ii) those that reduce or prevent viral replication and transmission. Each of these types of interactions is critical and both must be investigated to fully understand viral pathogenesis. Cells …
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Characterizing the early stages of a novel host shift using host fitness and metabolomics
… contribute to successful colonization of a novel host species by a pathogen remain unclear. One likely factor determining host shift success is the early interaction between host and pathogen at the very moment of the host shift event. How does a novel host respond to a pathogen insult immediately …
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