Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 20 for “"Hospitalised patients"”.
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Exploring structures and processes of medicines management in elderly hospitalised patients in the United Arab Emirates.
Given the complexity of medicines use in elderly patients, structures and processes of medicines management are key to deriving best outcomes. This research was conducted in hospitals in the United Arab Emirates (UAE) and focused on the patient journey from admission to discharge. The overall aim …
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Towards Phage Therapy: Characterization of Clostridioides difficile Bacteriophages from a South African Strain Collection
… persons with gastrointestinal dysbiosis, notably hospitalised patients on antibiotic therapy and those with other types of gastrointestinal conditions. This opportunistic infection is caused by a Grampositive, spore-forming bacillus, with conditions including diarrhoea, pseudomembranous colitis, …
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Addressing challenges in the treatment of tuberculosis and tuberculosis meningitis: a pharmacometric approach
… of drug resistance. Secondly, TB management in hospitalised patients becomes more difficult since they often face more advanced stages of the infection, as well as physiological changes that could impact the pharmacokinetics of anti-TB drugs. Lastly, TBM treatment is further complicated by …
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Utility of novel diagnostic tests for tuberculosis using human urine
… consisted of ambulatory primary care clinic patients suspected of having TB (group 1) whilst the second comprised hospitalised patients with suspected HIV co-infection (group 2). The urine LAM ELISA, LAM strip test and Xpert MTB/RIF were performed according to the manufacturer’s instructions. …
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A systematic review: the role of neuroinflammation as a pathway to injury in traumatic brain injury
… systems. We analysed and scored chest x-rays of hospitalised patients with HIV-associated tuberculosis and assessed the relationship of these chest x-ray scores with 12-week mortality and biomarkers of tuberculosis dissemination. Methods: In this cohort study, the chest x-rays of adult patients, …
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Towards implementation of pharmacogenomic-guided medicines optimisation for older patients in secondary care
… of pharmacogenomic (PGx)-guided care for older patients in secondary care. Using a mixed methods approach, the study demonstrates the efficacy of PGx-guided care for patients aged 65 and above, identifies behaviour change techniques for healthcare professionals to successfully adopt PGx-guided …
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The performance of respiratory illness surveillance case definitions to detect Bordetella pertussis in children aged < 5 years seeking healthcare for respiratory illness in South Africa, 2017-2023
… 2023. Participants were enrolled as either outpatients eligible for influenza‐like illness (ILI), or hospitalised patients eligible for severe respiratory infection (SRI) surveillance. Nasopharyngeal swabs were tested for B. pertussis using polymerase chain reaction (PCR). Sensitivity, …
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Improving point-of-care diagnosis of tuberculosis: development and evaluation of novel technologies
… (100%) and specificity (92%) for distinguishing patients with active TB from healthy controls. However, sensitivity (74%) and specificity (63%) were lower when the culture-negative participant group was compared to the culture-positive participants. The test shows potential as a useful screening …
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Prevalence, and outcomes of Rheumatic Heart Disease in Ethiopia: a systematic review and meta-analysis
… was per 21 per 1000 (95% CI, 12.27;32.03). In hospitalised patients, presentation included congestive heart failure, atrial fibrillation, and stroke. The 30-day mortality and post- operative mortality was 2.5 (95% CI, 0.00;12.81) and 32.8 (95% CI, 11.43;62.82) per 1000 respectively. The 60-day …
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The meaning of caring interpersonal relationships in nursing
This thesis explores nurses' and patients' perceptions of caring relationships in a hospital context. An attempt is made to discover the meaning these caring relationships have for the nurses who provide care and for the patients who participate in this process. The nurses enter into the caring …
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Advancing clinical practice in the management of Deep Vein Thrombosis: development, application and evaluation of the Autar DVT scale
Deep Vein Thrombosis (DVT) is a disease of hospitalised patients and is a precursor of Pulmonary Embolism (PE), a potentially fatal complication. DVT and PE are preventable and venous thromboprophylaxis consensus groups recommend that patients be risk assessed and accordingly receive appropriate …
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Characterisation of clinical and anatomical substrates in risk stratification and management of atrial fibrillation and ischaemic stroke
… of adverse cardiovascular outcomes in patients with non-valvular atrial fibrillation. Towards this end, three articles in this thesis evaluate a cohort of hospitalised patients with non-valvular atrial fibrillation. Study findings from this work identify structural adverse cardiac …
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Risk stratification in patients with heart failure and in patients with implantable cardioverter-defibrillators
… with significant mortality and morbidity. Patients hospitalised with heart failure are at high risk of death in the short term and patients with chronic heart failure in the community are also at a high risk of death in the medium to long term. It is difficult to accurately identify those …
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Prevalence and outcome of delirium amongst acute general medical inpatients in Cape Town, South Africa
… condition in acute medical and surgical inpatients. It is associated with increased risk of mortality and morbidity. Data are largely limited to developed countries in geriatric cohorts. Here we describe prevalence, risk factors and outcomes of delirium amongst general medical patients …
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Antibiotic use and the effect of prescribing guidelines in care of the elderly.
… guidelines on antibiotic prescribing in elderly, hospitalised patients. Three audits of antibiotic use were carried out, one before (n=324) and two after (n=302 & 263) the introduction of the antibiotic treatment guidelines. Three types of hospital bed were included in the audit: geriatric …
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Design, Synthesis and Evaluation of Organic and Metal Based Antimicrobial Agents
… have estimated that on any given day 1 in 18 hospitalised patients have a healthcare-associated infection (HAI) and that a large percentage of these infections are caused by resistant strains of bacteria. With the global spread of antibiotic-resistance and the emergence of bacteria resistant …
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Exploring medication error causality and reporting in the Middle East.
… nature and causes of medication errors among hospitalised patients in Middle Eastern countries. Findings indicated the lack of robust and rigorous research, both generally and also specifically in Qatar. There was a clear need for theory-informed primary research. The second phase collated …
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The development of a non-pharmacological intervention for delirium management in critically ill patients
Delirium is common in Intensive Care Unit (ICU) patients with incidence up to 74 % in the United Kingdom and is associated with increased mortality and morbidity. Multicomponent non-pharmacological interventions are beneficial in the prevention and treatment of delirium in older hospitalised …
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Factors contributing to falls in a tertiary acute care setting in Cape Town, South Africa: a descriptive study
… of the most common adverse events experienced by hospitalised patients. In-hospital falls have negative outcomes for patients, causing injuries in up to half of those who fall. Falls in hospital create additional costs for health services due to increased length of stay (LOS), and greater health …