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Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 16 of 16 for “"Hormones, Hormone Substitutes, and Hormone Antagonists"”.
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Assay procedures for dehydroepiandrosterone
<p>Dehydroepiandrosterone (DHEA) is a 17-ketosteroid which is produced by the adrenal cortex and is excreted in the urine as DHEAsulfate, In diseases of the adrenal cortex, such as adrenal carcinoma or adrenal hyperactivity, the level of DHEA-sulfate in the urine is increased. There are two …
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Improving dopamine monitoring with NCAM and the effects of intranasal oxytocin on dopamine signaling in the rat brain
<p>Dopamine (DA) is a neurohormone highly involved in learning and memory. Oxytocin (OXT), another neurohormone, has also been implicated in learning and memory. Fast-scan cyclic voltammetry (FSCV) is a method used for the real-time examination of DA neurotransmission in the brain. Implanting FSCV …
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The Involvement of Estrogen Receptors in Astrocyte Survival
<p>Estrogens are a class of hormones that are demonstrated to be neuroprotective. The levels of estrogen in the body decline during menopause which can cause a variety of symptoms. Hormone replacement therapy (HRT) is a treatment option for menopause, however, it has been demonstrated to have …
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Regulation of Luteinizing Hormone and Catecholamine Release
… the interrelated hypotheses that the ovarian hormones produce their positive feedback effects on luteinizing hormone (LH) secretion through activation of noradrenergic and adrenergic systems in specific hypothalamic regions. Furthermore, the ovarian hormones may alter the activity of opioid …
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Antibiotics and the Wasting Disease in Neonatally Thymectomized Rats
… Chloramphenicol, to pregnant rats just prior to, and for four days after delivery, diminishes the incidence of the so-called "Wasting Disease" in neonatally thymectomized rats.</p> <p>A total of 50 rats were divided into the following groups:</p> <ol> <li>Thymectomy only---nonmedicated 17 …
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Effect of 9 α-fluorohydrocortisone Acetate on Gastric and Salivary Electrolytes of Normal Fasting Subjects
… effect of 9α-FF on the Na:K ratio, chloride, and pH of saliva and gastric secretions, and on the total and free acid of gastric juice in normal human subjects was investigated. This study was designed to investigate whether conditions could be produced in the normal human subject similar to …
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Effects of Furosemide and Oleic Acid On Thyroxine Binding to Isolated Pairs of Thyroxine Binding Serum Proteins
<p>Dosage dependent binding inhibition and redistribution of thyroxine (T<sub>4</sub>) between three pairs of thyroxine binding serum proteins, TBG-TTR, TBG-albumin and TTR-albumin, by furosemide (0.0 to 1.0 mol/L) and oleic acid (0.0 to 0.10 mol/L) were studied using equilibrium dialysis with …
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Sex Differences in Nicotine-Conditioned Hyperactivity in a Model of Dopamine D2 Receptor Priming: Roles of Dopamine D2 and D3 Receptor Subtypes.
… hyperactivity in an animal model of D2-priming, and whether conditioned hyperactivity could be blocked by the D2 antagonist eticlopride or the D3 antagonist nafadotride. D2-primed male rats showed enhanced nicotine sensitization as evidenced by statistically significant differences in horizontal …
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Insulin and Glucagon Responses to Dietary Protein in Diabetic and Nondiabetic Men
… men with non-insulin-dependent diabetes mellitus and fourteen nondiabetic men, were given test meals with soy protein, casein or additional carbohydrate in place of protein. Blood levels of insulin, glucagon, glucose and lipids were measured at fasting, one-half hour and two hours postprandial. To …
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Interaction of Putative Estrogens and the Estrogen Receptor System in Leydig Cells in the BALB/c Mouse Testis Resulting in the Initiation of DNA Synthesis
… of estrogens for 7-9 months, both steroidal and nonsteroidal, to male BALB/c mice, leads to the formation of testicular Leydig cell tumors. Three days following the subcutaneous implantation of a pellet of estrogen in cholesterol, there is a peak in the incorporation of <sup>3</sup>H-tymidine …
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Decreased Triiodothyronine Binding to the Hepatic Nuclear Thyroid Hormone Receptor in the Diabetic Mouse
… m</em> mouse has abnormal thyroid hormone levels and indications of thyroid hormone resistance. To investigate the basis of these abnormalities, the hepatic nuclear thyroid hormone receptor was extracted with 0.4 M KCl, 1.1 mM MgCl<sub>2</sub>, 20 mM Tris/HCl, pH 7.9 from hepatocyte …
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The Relationship Between Vitamin D Status of Adult Women and Diet, Sun Exposure, Skin Reflectance, Body Composition, and Insulin Sensitivity
… disease strengthens suggesting vitamin D’s candidacy in the prevention and treatment of multiple disease states and their complications. Dietary guidelines, however, do not take sun exposure into account. The present study sought to explore the impact of sun exposure on vitamin D status …
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Modelling Β2Ar Regulation
… smooth muscle relaxation in the vasculature and airways. Long- and Short-acting β-agonists (LABAs/SABAs) are widely used in treatment of chronic obstructive pulmonary disorder (COPD) and asthma. Despite their widespread clinical use we do not understand well the dominant β2AR regulatory …
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The Effect of Radiation and Repeated Sub-culturing on TGF-β1 Signaling in FRTL-5 Cells
… accelerated growth, reduced follicularization and reduction in thyroxin release that occurred as the cells were repeatedly sub-cultured. We also recorded that these changes occurred earlier and more rapidly following radiation exposure. We determined that TGF-β1 production increased under both …
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Self-reported Exercise and Risk of Osteoporosis in Prostate Cancer Patients Receiving Androgen Deprivation Therapy
… stimulated to grow in response to testosterone. Androgen deprivation therapy (ADT) leads to chemical castration and suppression of prostate cancer cell production. Testosterone levels less then 300ng/ml decreases bone mineral density and could result in osteoporosis. Studies have shown that …
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Identifying a Glucocorticoid-activated GPCR that Rapidly and Non-Genomically Increases cAMP Levels in Mammalian Cells
<p>Glucocorticoids (GCs) are steroid hormones that regulate diverse physiological processes. Synthetic versions of GCs are commonly used to treat inflammatory diseases such as asthma by modulating gene expression to suppressing several inflammatory activities. However, it is estimated that 5-10% of …