Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 15 of 15 for “"Homologation"”.
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Catalytic one-carbon homologation of alkenes
… chemical properties brought about by one-carbon homologation can have profound impacts on the physiochemical properties of functional molecules, including pharmaceutical agents, natural products, agrochemicals and fragrances. Consequently, the development of efficient and direct methods for …
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New strategies for the synthesis and homologation of complex aliphatic amines
… example of a direct, catalytic method for the homologation of benzylic tertiary amines to higher-order ω-aryl alkylamines is detailed. The one-carbon homologation reaction was found to be general across a broad range of substrates (>50 examples), including a variety of representative …
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I Progress towards the synthesis of plakortether B through a zinc-mediated homologation II Synthesis of novel hydroxy-cyclopropyl peptides isosteres
… core of plakortether B through a zinc-mediated homologation-aldol reaction has been developed. This chemistry was performed on a chiral beta-keto amide, which was synthesized in a few steps. In a one-pot reaction the beta-keto amide could be converted into a furanyl-ketal with high stereocontrol …
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I The tandem chain extension-acylation reaction II Synthesis of papyracillic acid A: Application of the tandem homologation-acylation reaction III Synthesis of tetrahydrofuran-based peptidomimetics
… as a variety of acylating agents. The tandem homologation-acylation reaction was successfully applied towards the total synthesis of papyracillic acid A.</p><p>Use of a tandem chain extension-aldol reaction, followed by a reductive cyclization, allowed for the synthesis of …
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The development of iterative and cascade methods for the rapid synthesis of ladder polyether natural products
… An iterative method comprising chain homologation, epoxidation, 6-endo cyclization, and protiodesilylation was developed. Notable achievements include the development of a novel propargyl organocopper coupling method, and the complete control of stereoselectivity and regioselectivity …
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Synthetic studies towards total synthesis of bielschowskysin
… centre. In order to form the lactone, Wittig homologation with methyl (triphenylphosphoranylidene) acetate followed by hydrogenation and TBAF mediated cyclisation was performed. Regarding right fragment, our initial approaches were unsuccessful due to scalability and decomposition. Thus …
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Development of an Electronic Stability Control for Improved Vehicle Handling using Co-Simulation
… passes the regulations that describes the ESC homologation process for North America and European countries, each defined by National Highway Traffic Safety Administration (NHTSA) and United Nations (UN). The proposed research project will enable automotive engineers and researchers to perform …
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L'homologation judiciaire des conventions. Essai d'une théorie générale.
Lorsqu’il recourt à la technique de l’homologation en matière contractuelle, le législateur permet ou impose aux parties qu’aucun litige n’oppose (plus), de soumettre leur convention au contrôle d’un juge. Bien que la décision que le juge rend à l’issue de ce contrôle soit susceptible de modifier …
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Quinone-Catalyzed Amine α-C–H and α-C–C Functionalization
… In this regard, we developed a novel method for homologation of aromatic α-amino acids through sequential quinone-catalyzed oxidative decarboxylation/Mukaiyama−Mannich addition under mild reaction conditions. Following this discovery, quinone-catalyzed deformylative functionalization of aromatic …
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Educazione indigena in Perù. Il concetto di interculturalità e la sua applicazione nell’elaborazione del materiale didattico
… times, despite being an instrument for cultural homologation and assimilation since the beginning, the school has undertaken an important role for the indigenous populations within the process of knowledge decolonization and the power relationships overrunning the national reality.
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Synthetic studies toward 6-deoxy-ß-D-ido-heptopyranosides related to capsular polysaccharides of Campylobacter jejuni
… to occur at a much improved rate. Finally, homologation of the β-D-idopyranoside at C-6 was studied which enabled access to two analogues of target β-D-ido-heptopyranoside (Chapter 5). Future work will involve the development of efficient methodologies to introduce the 6-deoxy-7-hydroxy …
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Boron-Mediated Semireduction of Alkynoic Acid Derivatives
… the Chan-Evans-Lam cross-coupling, lithiation-homologation, allylboration, and many other reactions rely on boron to achieve otherwise difficult chemical transformations. Thus, developing novel methods towards the regio- and/or stereoselective installation of boron into organic molecules remain …