Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 3 of 3 for “"Homogentisate"”.
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Identifizierung und Charakterisierung von Homogentisat-Prenyltransferasen aus dem Tocopherol- und dem Plastochinon-9-Biosyntheseweg
… biosynthesis of these compounds is catalyzed by homogentisate prenyltransferases located in the inner envelope membranes of chloroplasts. These enzymes use homogentisate derived from the shikimate pathway and prenyl diphosphates synthesized via the plastidial non-mevalonate isoprenoid pathway as …
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Consequences and Prevention of Elevated Circulating Tyrosine during Nitisinone Therapy in Alkaptonuria.
… tyrosine catabolism due to mutations within the homogentisate 1,2-dioxygenase (HGD) gene. The resulting enzyme deficiency leads to accumulation of homogentisic acid (HGA) and deposition of melanin-like pigment polymers in the connective tissues of the body in a process called ochronosis. This …
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The effects of superoxide dismutase on osteoarticular cells and structural analysis of ochronosis, in a disease model of alkaptonuria
… recessive condition resulting from deficiency of homogentisate 1,2 dioxygenase, causing inability to metabolise homogentisic acid (HGA). Over time HGA polymerises and deposits as a dark pigment within collagenous tissues; this process is ochronosis. Ochronosis causes rapid and early onset joint …