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Showing 1 to 12 of 12 for “"Homocysteine (Hcy)"”.
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C-Reactive Protein, Homocysteine, And Cognitive Performance In Healthy Adults
… blood levels of C-reactive protein (CRP) and homocysteine (Hcy) have received a great deal of attention as biomarkers for the development of cardiovascular disease. Their utility in predicting cognitive function has also been assessed, though the findings are equivocal. The current study …
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The Role of Potassium in Betaine-Homocysteine Methyltransferase
Homocysteine (Hcy) is an intermediate of methionine metabolism and acts as a critical branch point between protein synthesis and numerous regulatory pathways in the cell. Elevated plasma total Hcy (tHcy) is associated with an increased risk for cardiovascular disease, although the mechanism by …
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Bioanalytical methods for studies of homocysteine and novel cardiovascular disease indicators
… to investigate the chemical reactivity of homocysteine (Hcy), an independent CVD risk factor and serological biomarker. Consequently, we proposed an alternate theory for in vivo Hcy clearance based on spontaneous pyridoxal tetrahydrothiazine (PT) formation from Hcy and pyridoxal. The …
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Regulation of mTORC1 by homocysteine and its effects on autophagy in human and mouse neuronal tissues
… elevated levels of the amino acid metabolite homocysteine (Hcy) are at high risk of developing AD. The impact of Hcy on molecular clearance pathways in mammalian cells, including in-vitro cultured induced pluripotent stem cell-derived forebrain neurons and in-vivo neurons in mouse brains is …
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Two Sides of The Same Coin in The Levodopa Treatment of Parkinson's Disease
… and apoptotic pathways. Second, the CSF total homocysteine (Hcy) concentration was higher in patients with PD before L-dopa treatment than in controls, and Hcy concentration increased after administration of L-dopa. Elevation of the Hcy concentration in plasma has been implicated in …
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Correlation of Homocysteine Concentration with Plasma Fibrinogen and Physical Activity in Males with Coronary Artery Disease
Elevated homocysteine (Hcy) concentration has been identified as an independent risk factor for premature CAD. Associations between Hcy concentrations and established cardiovascular risk factors have occasionally, but not consistently, been demonstrated. Plasma fibrinogen and total Hcy …
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Direct detection of homocysteine and syntheses of lanthanide complexes as biosensors
At elevated levels, homocysteine (Hcy) is a risk factor for cardiovascular diseases and Alzheimer’s disease. It’s also implicated in a number of other diseases such as neural tube defects, pregnancy complications, and renal failures. The monitoring of Hcy levels in plasma is of current concern. To …
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Detection of Biologically Important Molecules
… anions remain colorless. The monitoring of homocysteine (Hcy) and cysteine (Cys) levels is important since they are biomarkers associated with Alzheimer’s and cardiovascular disease, among many others. In the second chapter, the selective detection of Hcy and Cys over other amino acids using …
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New Insights Into the Structure and Function of Betaine-Homocysteine S-Methyltransferase
… of patients have elevated levels of plasma total homocysteine (Hcy), which is now considered a risk factor for cardiovascular disease, stroke, and Alzheimer's disease. Endothelial damage may be caused by Hcy-induced vascular oxidative stress. Hcy is not a dietary amino acid, but is an important …
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Mechanisms responsible for homocysteine mediated damage to human endothelial cells : the role of oxidative stress in atherogenesis.
Homocysteine (Hcy) has been identified as a primary risk factor for atherosclerosis as it induces endothelial cell (EC) activation/dysfunction and thus potentially initiating atherosclerotic plaque formation. There is accumulating evidence indicating a key role for oxidative stress in mediating Hcy …
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Sex differences in the associations of physical fitness, physical activity, sedentarism, and sleep behaviour with oxidative stress in older adults: The INTERMAE project
… the excessive production of oxidants (such as homocysteine, HCY) and the inability of the total antioxidant capacity (TAC) of the body to cope with them. When this condition occurs an accumulation of oxidatively damaged macromolecules appears, leading to the loss of function of these …
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Biochemical markers of hypertension and chronic renal failure in a Gulf Arab population of the United Arab Emirates
… levels of immunoreactive endothelin-1 (ET-l), homocysteine (Hcy), growth hormone (GH), insulin-like growth factor-I (IGF-l), leptin, and insulin were measured by standard enzyme-linked immunosorbent assay (ELISA) methods. Plasma glucose, blood urea nitrogen (BUN), creatinine, lipids and …