Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 11 of 11 for “"Homeodomain Proteins"”.
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Investigation of Interactions between Homeodomain Proteins and DNA
… zu aggregieren, wenn die Konzentration des Proteins in der Lösung dieses stöchiometrische Verhältnis überschreitet. Die kinetischen Daten der Bindung der Bcd- und Ubx-Homeodomänen an DNA sind im Einklang mit einem zweistufigen Reaktionsmechanismus. Im ersten Schritt bildet sich ein …
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Analysis of Plant Homeodomain Proteins and the Inhibitor of Growth Family Proteins in Arabidopsis thaliana
… closed status of chromatin. The PHD (Plant HomeoDomain) finger is a structural domain primarily found in nuclear proteins across eukaryotes. This domain specifically recognizes the epigenetic marks H3K4me2 and H3K4me3, which are di- and tri-methylated lysine 4 residues of Histone H3 (Loewith …
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Downregulation of reproductive homeobox gene 6 (RHOX6) interferes with male germ cell differentiation
Homeodomain proteins contain a 60 amino acid DNA binding motif called homeobox that regulates a variety of developmental events. Recently, a novel cluster of homeobox genes has been discovered on the X chromosome of the mouse. Because of their selective expression in reproductive organs, they are …
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WHO: A Novel Wuschel-Like Homeodomain Transcription Factor in Arabidopsis
We have isolated a novel homeodomain transcription factor gene in Arabidopsis. It shares a high degree of identity with WUSCHEL (WUS), a transcription factor involved in specifying stem cell fate in shoot and floral meristems among several plant species. This novel homeobox gene, designated as …
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Examining the effect of CBP on the E2A-PBX1 and HOXB4 interaction
… cofactor for most members of the HOX family of homeodomain proteins and is necessary for regulating the essential role that HOX proteins play in development and tissue homeostasis. We have identified an interaction between the E2A-encoded portion of E2A-PBX1 and the CREB-binding domain (KIX) of …
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Role of Xenopus Pitx3 during early development.
Pitx homeodomain proteins are highly conserved regulatory proteins that were first discovered on the basis of their involvement in the transcriptional regulation of pituitary-specific genes. Recently, a third member of Pitx family, Pitx3, has been identified which expresses in the midbrain and eye. …
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Co-factors of LIM-HD transcription factors in neural development and axon pathfinding in zebrafish
… LIM domain transcription factor signaling. LIM homeodomain proteins (LIM-HDs) are an important class of transcriptional regulators and involved in neural development as well as neuron fate decision in vertebrates. DD domain dimerization of CLIM (cofactor of LIM-HDs) can activate LIM-HDs and …
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MEIS1: At the Crossroads Between Metabolic and Cell Cycle Regulation
Stem cells undergo self-renewal, maintaining themselves in an undifferentiated state while generating differentiated cells that are required for the tissue homeostasis or repair. One intriguing feature of stem cells is their maintenance in their respective hypoxic niche. Survival in this low-oxygen …
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Die frühe Infektionsphase von Ustilago maydis
… by the multiallelic b-locus, encoding two homeodomain proteins, bW and bE. After fusion of haploid sporidia, bW and bE proteins from different alleles can form heterodimers, triggering downstream cascades of regulatory processes. These control filamentous growth, penetration of the plant …
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Elucidating the Role of Cellular Architecture in the Developing Pancreas
Many studies have focused on examining the intrinsic factors such as transcriptional regulators that instruct the step-wise acquisition of β-cell fate in the developing pancreas, with the intention of recapitulating the events necessary in order to generate these cells in vitro for replacement …
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The Influence of DNA Methylation on Both H2A.Z Nucleosome Dynamics and the Zinc Finger and Homeoboxes Transcription Factor Family
… DNA methylation has on two classes of chromatin proteins, the histone variant H2A.Z and the Zinc Finger and Homeoboxes (ZHX) family of transcription factors. DNA methylation and H2A.Z preferentially occupy exclusive areas of the genome, biasing against their colocalization in the same genomic …