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Showing 1 to 3 of 3 for “"Hollow fiber bioreactor"”.
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Characterization of a new miniaturized hollow-fiber bioreactor for cultivation of cell lines and primary cells to improve cytostatic drug testing in vitro
… models. In the present work, a new miniaturized hollow-fiber bioreactor system for mammalian cell culture in small volumes (up to 3 ml) is characterized with regard to transport characteristics and growth of leukemic cell lines (chapter 2). Cell and medium compartment are separated by dialysis …
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Biocapacitance Sensors for In-Line Viable Cell Density Monitoring in Complex Bioreactors
… monitoring of Viable Cell Density (VCD) in bioreactors is crucial for optimizing bioprocesses, improving yield, and maintaining product quality. VCD can be effectively indicated by biocapacitance, a capacitance associated with the viable cell membrane, which can be detected through …
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Design and Analysis of Methods to Eliminate Oscillatory Behavior in Bioreactors for Viral Vaccine Manufacturing
… novel reactor designs. One such design, a novel hollow fiber bioreactor, is explored in this work. This design constrains larger cellular and viral species within a hollow fiber lumen where viral infection of the cells can take place along the length of the reactor. Fresh media is provided to the …