Global ETD Search
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Showing 1 to 2 of 2 for “"Histone arginine methylation"”.
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The Regulation of Dna Methylation In Mammalian Development and Cancer
<p>DNA methylation is an essential epigenetic modification in mammals, as it plays important regulatory roles in multiple biological processes, such as gene transcription, maintenance of chromosomal structure and genomic stability, genomic imprinting, retrotransposon silencing, and X-chromosome …
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Gain-of-Function Mouse Models to Investigate Biological Roles of Prmt6
… <p>Mentor: Dr. Mark T. Bedford</p> <p>Protein Arginine Methyltransferase 6 (PRMT6) is the histone tail writer that methylates the H3R2 (arginine 2 of histone H3) residue, which counteracts the activating H3K4me3 mark. PRMT6 has been shown to behave both as transcriptional co-repressor (i.e. …