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Showing 1 to 1 of 1 for “"Histone H3 methylatio"”.
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Upstream conserved sequence element that regulates TIM-3 induction in CD4+ T cell
… mouse and cow counterparts. Only at CNS -63, H3K4 dimethylation that is associated with transcriptional activation was observed in Jurkat T cells and CD4+ T cells isolated from human blood. Further, CNS -63 increased luciferase reporter gene expression downstream of TIM-3 minimal promoter. …