Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 2 of 2 for “"Histocompatibility Antigens Class I"”.
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Functional Characterization of the HIV-1 NEF Acidic Cluster
… including: (1) the downregulation of major histocompatibility complex I (MHC-I), (2) the downregulation of CD4, (3) infectivity enhancement, and (4) Pak2 activation. These in vitro effects, with the exception of CD4 downregulation, rely in part upon Nef's acidic cluster which has been …
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Targeting the Neonatal Fc Receptor, FcRn, to Treat Autoimmunity and Elucidation of Sites of FcRn Function
… Using very low doses of these engineered antigens to avoid anaphylactic shock, the study demonstrates that the longevity of the peptide antigen is the primary determinant of tolerance induction in a murine EAE model that is driven by autoreactive CD4+ T cells. Long-lived Fc-antigen fusions …