Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 181 for “"Histocompatibility"”.
-
Structural Analyses of Murine Histocompatibility Antigens
<p>The major histocompatibility antigens are the predominant cell surface molecules recognized by the immune system in the rejection of grafts between individuals of the same species. The genes coding for the histocompatibility antigens are extremely polymorphic; the products of different alleles …
-
The Major Histocompatibility Complex in Rabbits
… processes as they take place. The major histocompatibility complex (MHC) is a key component of the immune system’s response to both fight disease and maintain health. Present in all jawed vertebrates, the MHC has played a key role in immunocompetence for over 400 million years. Its …
-
The genomic anchors of the human major histocompatibility complex
… The aim of this thesis is to use the human Major Histocompatibility Complex (MHC) as model region to provide novel insights into the relationship between chromatin folding mediated by MARs and gene expression. This large locus contains critical genes for immunity and is associated with more …
-
Diversity and Evolution in the Avian Major Histocompatibility Complex
… commercial poultry industry. The chicken Major Histocompatibility Complex (MHC) has been particularly well-studied, since variation at the chicken MHC is strongly associated with resistance and susceptibility to disease, particularly infectious pathogens. Furthermore, its 'minimal essential' …
-
Identification of major histocompatibility complex haplotypes in goldfish, Carassius auratus
… for observing variability at the major histocompatibility complex (MHC) of fishes could prove an important first step in understanding the genetic bases of disease resistance. In this study, using goldfish (Carassius auratus) as a model system, three approaches to generating antisera to …
-
Control of major histocompatibility Class I antigen expression in adenovirus transformed cells.
… CRE1 and CRE2, located upstream of the Major Histocompatibility Complex (MHC) class I gene have been shown to play an important role in controlling transcription of this gene. MHC class I expression is down-regulated in cells expressing Adenovirus (Ad) 12 E1A compared to cells expressing E1A …
-
Associations of egg production with the major histocompatibility complex in broiler breeder hens
This study documents effects of the major histocompatibility complex (MHC) on reproductive traits in a flock of Cobb X Cobb broiler breeder hens. The objective was to determine if the MHC affects reproduction of non-congenic broiler breeder hens. Genomic DNA was isolated from 35 hens. Restriction …
-
Characterization of leukemia - associated minor histocompatibility antigens as targets in anti-leukemic immunotherapy.
Contains fulltext : 30117_charoflea.pdf (Publisher’s version ) (Open Access)
-
Insight into the structure and function of empty class II major histocompatibility complexes
Class II major histocompatibility complex (MHC) proteins bind peptides and present them at the cell surface for interaction with CD4+ T cells as part of the system by which the immune system surveys the body for signs of infection. Peptide binding is known to induce conformational changes in class …
-
Structure studies of the human class II major histocompatibility complex protein HLA-DR1
Major Histocompatibility Complex (MHC) proteins are heterodimeric membrane glycoproteins that bind antigens in the form of short peptides within the cell and present them to the T cell receptors on the surface T cells. In this thesis work, the structural aspects of the human class II MHC protein …
-
Modulation of Ly49A+ Natural Killer Cell Licensing by Major Histocompatibility Complex Class I Alleles
… that react to cells lacking self-MHC: major histocompatibility complex) class I molecules, such as transformed or virally infected host cells and allogeneic bone marrow. This reactivity is mediated by inhibitory receptors for MHC class I that block the ability of activation receptors to …
-
Identification and characterization of a chicken major histocompatibility complex class II[beta] gene promoter
<p>The major histocompatibility complex (MHC) contains a variety of genes. Among them, the class II genes encode proteins involved in antigen presentation to helper T cells, a key step in initiating immune responses. The regulation of class II gene expression has been extensively studied in …
-
The Major Histocompatibility Complex (MHC) and the proteasome-ubiquitin pathway in T cell development
The essential role of classical MHC molecules in T cell development as well as the proteasome role in antigen processing for MHC-mediated antigen presentation to T cells is well established. However, the contribution of nonclassical MHC molecules, the signals evoked by the MHC-TCR interactions, the …
-
Major histocompatibility complex diversity in an urban Chacma baboon (Papio ursinus) population: Implications for conservation
Since the 15th century, human activity has altered and degraded nearly half of the available land of the Cape Peninsula, South Africa; this has resulted in significant restriction and fragmentation of the historic geographic range of the peninsula's Chacma baboon (Papio ursinus) population.
-
The folding, assembly, and intracellular transport of murine class I major histocompatibility complex heavy chains
Thesis (Ph. D.)--Massachusetts Institute of Technology, Dept. of Biology, 1997.
-
MAJOR HISTOCOMPATIBILITY COMPLEX (MHC) VS NON-MHC INFLUENCES ON RESPONSE TO RSV-INDUCED TUMORS IN CHICKENS
<p>The MHC of the chicken (B complex) has been shown to exert a decisive influence on the fate of Rous sarcoma virus (RSV)-induced tumors. However, noninbred chickens with identical B genotypes and inbred lines indistinguishable at the MHC have demonstrated considerable variation in response to RSV …
Page 1 of 10