Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 33 for “"Hippocampus (Brain)"”.
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Anatomical and Functional Characterization of the Ventral Hippocampus in a Rodent Model of Schizophrenia Neuropathology
… no cure. Many studies have implicated the hippocampus and the parahippocampal region as a place of both primary pathology in the disease and as regions correlated to symptom severity. To better understand the pathophysiology of the region and potentially uncover mechanisms of the disease, …
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Impact of adult hippocampal neurogenesis on behavior
… was arrested using focal x-irradiation of the hippocampus, or a reversible, genetic method in which glial fibrillary acidic protein-positive neural progenitor cells are ablated with ganciclovir. Arresting neurogenesis did not alter general activity or object investigation during four exposures …
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Microsystem Based on CMOS Multielectrode Array for Extracellular Neural Stimulation and Recording
Neurobiology is constantly in search of new tools and techniques to extract structural and functional information from neural circuitry. Conventional electrophysiological stimulation and measurement technique such as patch clamping have become the standard techniques for accurate stimulation and …
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Large-scale Functional Connectivity in the Human Brain Reveals Fundamental Mechanisms of Cognitive, Sensory and Emotion Processing in Health and Psychiatric Disorders
… networks that integrate remote areas of the brain as working functional units are thought to underlie fundamental mechanisms of perception and cognition, and have emerged as an active area of investigation. However, traditional approaches of measuring functional connectivity are limited in …
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Role of Microtubule Motor Proteins in Adenoviral Infections
Viruses have been described as a piece of nucleic acid surrounded by bad news. These bad news determine host specificity, pathogenicity, and virulence. In the case of adenovirus, a non-enveloped double-stranded DNA virus that causes self-limiting disease in healthy individuals but can cause severe …
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Functional Characterization of Hippocampal Synapses in a Mouse Mutant of the Dystrobrevin Binding Protein 1 (DTNBP 1) Gene
Genetic variation in the dystrobrevin binding protein 1 (DTNBP1) gene has been linked to cognition and neurological diseases such as schizophrenia and bipolar disorder. Unfortunately, the neuronal function of the encoded product, dysbindin, is poorly understood. Many reports have claimed that …
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Aberrant assembly and function of a hippocampal circuit in a genetic mouse model of schizophrenia
… is highly expressed in the dentate gyrus of the hippocampus of adult mice, a region that is important for learning and memory. Disc1Tm1Kara mutant mice have specific deficits in spatial working memory, a process that requires the interconnectivity of the hippocampus and prefrontal cortex. …
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Mast cells affect brain physiology and behavior
Mast cells are immune cells that are found in the brain. Behavioral and endocrine states increase the number and activation of brain mast cells, independent of the animal's immune status. Activation causes the release of many neuro-active mediators into the brain parenchyma. However, the function …
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