Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 21 for “"Hild"”.
-
A tale of two proteins: relationship between HilD & FliZ in SPI1 regulation
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2027-08-01
-
Regulation of Salmonella pathogenicity island I through the hilD mRNA 3' untranslated region
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2025-05-01
-
Studies on the control and activity of the Salmonella spi-1 regulator HilD
Submission original under an indefinite embargo labeled 'Open Access'. The submission was exported from vireo on 2022-04-06 without embargo terms
-
Integration of small RNAs in the control of Salmonella pathogenicity island 1(SPI1)
… effector proteins. Three AraC-like regulators, HilD, HilC, and RtsA, form a feed-forward regulatory loop that activates transcription of hilA. Many environmental signals and regulatory systems are integrated into this circuit to precisely regulate SPI1 expression. Our previous genetic analyses …
-
Mechanisms of signal integration: Regulation of the SPI1 T3SS
… is controlled by three AraC-like regulators HilD, HilC, and RtsA, which form a complex feed forward loop to activate expression of hilA, encoding the main transcriptional regulator of T3SS structural genes. This system is tightly regulated, with many of the activating signals acting at the …
-
Regulation of the Salmonella Pathogenicity Island 1 Type Three Secretion System
… and engulfment of the bacteria. HilC, HilD, and RtsA activate expression of SPI1 genes by binding upstream of the master regulatory gene hilA to induce its expression. HilA activates the SPI1 T3SS structural genes. Here I present evidence that hilA expression, and hence the SPI1 T3SS, …
-
Regulation of virulence in Salmonella enterica
… T3SS in the cell. Three AraC-like regulators, HilD, HilC, and RtsA, directly activate hilA expression, as well as each other and themselves, forming a complex feed-forward regulatory loop to control SPI1 expression. The production of the SPI1 T3SS system is tightly controlled, with many …
-
The Role of Periplasmic Disulfide Bond Status in the Regulation of the Salmonella SPI1 Type Three Secretion System
… directly by three AraC-like regulators: HilD, HilC and RtsA. A periplasmic disulfide bond oxidoreductase DsbA is required for SPI1 T3SS function. RtsA directly activates dsbA and deletion of dsbA leads to loss of SPI1-dependent secretion. We have studied the dsbA phenotypes by monitoring …
-
Coordinate Regulation of Salmonella Virulence Gene Expression During Infection
… hilA expression. RtSA also induces expression of hilD, hilC, invF, and slrP. RtsA induction of these genes is independent of other SPI1 regulators. RtsA directly induces hilA expression by binding to the promoter. We propose that RtsA, HilC and HilD form a feed forward regulatory loop, because …
-
Understanding small RNA-mediated post-transcriptional regulation of Salmonella pathogenicity island 1 activator HilA in Salmonella typhimurium
… functioning to counteract HilA overactivation by HilD. This work revealed the structure of sRNA regulatory networks controlling SPI-1. Expression of master regulators such as HilD is extensively targeted by multiple sRNAs, while downstream effectors like HilA receive minimal direct …
-
Influence of Physiological State, Prolonged Dry Storage, and Passage through Simulated Digestion on the Survival and Gene Expression of Salmonella enterica sv. Tennessee
… stress response (rpoS, otsB), virulence (hilA, hilD, invA, sipC) and a housekeeping gene 16S rRNA using quantitative real-time PCR. The physiological state and length of storage effected the survival and gene expression of Salmonella within the desiccated milk powder environment and after …
-
Haupt- und Spurenelementchemismus von Unterkreidesedimenten (Apt / Alb) aus dem Niedersächsischen Becken
Die vorliegende Dissertation befaßt sich mit der hochauflösenden anorganisch-geochemischen Untersuchung von Sedimenten der borealen Unter-Kreide (Apt/Alb) Nordwestdeutschlands. Mittels RFA, Coulometrie, ICP-MS und weiterer Methoden wurden ca. 550 Proben zweier Kernbohrungen (Kirchrode II/94, …
-
Towards formative interpretation: a theological hermeneutical proposal
How can we read the Bible to be formed as readers? This question opens a number of possible avenues of academic inquiry, but the one taken in this paper is mainly concerned with hermeneutical questions of how we read the Bible and whether we can formulate a hermeneutical framework for formative …
-
A pilot plant study of the anaerobic digestion of semi-chemical mill wastes
The purpose of this investigation was to determine if high loadings of semi-chemical pulp mill waste could be processed in a pilot plant by anaerobic digestion.
-
Brides of Christ, royal marriage and the conversion of the English in Bede’s Historia Ecclesiastica
… book. Chapter Five considers Bede’s account of Hild and her role in the Northumbrian Church, as her life spanned the most important decades in its early development and she personally knew many of the most significant figures of this period. It will continue to demonstrate that various other …
-
Natural product discovery in actinomycetes and investigation into the regulation of SPI-1 in salmonella typhimurium
Submission published under a 24 month embargo labeled 'Closed Access', the embargo will last until 2026-08-01
Page 1 of 2