Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 20 of 35 for “"High-intensity focused ultrasound"”.
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Passive monitoring of high-intensity focused ultrasound
High intensity focused ultrasound (HIFU) can provide a means of noninvasive ablation or hyperthermia of tissues such as tumors. Real-time monitoring of the progression of the field distribution of the HIFU transducer during treatment is important for localizing the intersection of the beam with the …
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Effects of high intensity focused ultrasound on the intervertebral disc
… of this study was to study and try to optimise high intensity focused ultrasound treatment of the intervertebral disc. We demonstrated that it was possible to heat intervertebral discs with HIFU delivered by 50 or 5 mm diameter ultrasound transducers. Finite element studies indicated that it …
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Shear-wave imaging guidance for high-intensity focused ultrasound therapy
High-intensity focused ultrasound (HIFU) has attracted many research interests during the last three decades (since 1980s) for the precision of this treatment in the field of medical oncology and brain surgery. Even though the precision of HIFU application/exposure is particularly high, the overall …
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Dynamics of smart materials in high intensity focused ultrasound field
… dissertation addresses this requirement by using high intensity focused ultrasound (HIFU) as the external trigger. HIFU has a unique capability of maintaining both spatial and temporal control and propagating over long distances with reduced losses, to achieve the desired response of the smart …
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Optimized pulsing of high-intensity focused ultrasound for enhanced therapeutic window
High intensity focused ultrasound (HIFU) provides a unique modality to perform non-invasive surgeries. The thermal ablation technique relies on focusing the non-ionizing acoustic wave within soft tissues to produce a small lesion. HIFU operations are typically attempted by continuous-wave (CW) …
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Propagation of High Intensity Focused Ultrasound through a Patient-specific Ribcage Model
A method of 3D modelling of high intensity focused ultrasound (HIFU) treatment through ribcage using patient data is described. This is further tested experimentally to derive at various parameters which could be indirectly useful in defining amount of energy and alteration needed in treatment …
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Multi-functional Holographic Acoustic Lenses for Modulating Low- to High-Intensity Focused Ultrasound
Focused ultrasound (FUS) is an emerging technology, and it plays an essential role in clinical and contactless acoustic energy transfer applications. These applications have critical criteria for the acoustic pressure level, the creation of complex pressure patterns, spatial management of the …
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Cavitation monitoring and spatial mapping for pulsed high-intensity focused ultrasound enhanced drug delivery
High intensity focused ultrasound (HIFU) is an emerging non-invasive ablation modality, in which high amplitude ultrasound waves are focused inside the human body to thermally ablate or mechanically disrupt the tissue at the focus. Ultrasound-enhanced drug delivery is an active and promising area …
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Computation Of Acoustic Ressure Fields Produced In Feline Brain By High-Intensity Focused Ultrasound
… were numerically simulated for a spherically focused, nominally f1-transducer (focal length = 13 cm) at increasing values of the source pressure at frequencies of 1, 3, and 9 mhz. The corresponding focal intensities were correlated with the experimental data of Dunn et al. The focal pressure …
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Mechanical High-Intensity Focused Ultrasound (Histotripsy) in Dogs with Spontaneously Occurring Soft Tissue Sarcomas
… Histotripsy is a non-thermal, non-invasive high-intensity focused ultrasound (HIFU) ablative technique that causes mechanical fragmentation of tissue, resulting in liquefied acellular debris with histologically clear demarcated boundaries between treated and non-treated tissues. The …
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Investigation of Microstructure of Uterine Fibroids in Magnetic Resonance guided High Intensity Focused Ultrasound Therapy
… pelvic pressure, and discomfort. MR guided high intensity focused ultrasound (MRgHIFU) uses MRI to monitor thermal ablation of uterine fibroids. It is non-invasive and requires a short recovery time. However, MRgHIFU therapy has several challenges: (1) The long pre-imaging time, which …
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Development of positioning devices for MRI-guided high intensity focused ultrasound (HIFU) for abdominal, thyroid and brain, tumours
High intensity focused ultrasound (HIFU) is a promising technology for a variety of therapeutic applications. This concept initiated in 1942 by Lynn Zwemer [1]. HIFU has long been known as a minimal invasive or non-invasive procedure that destroys tissue through ablation. However, it is only in …
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Experimental Study of Advanced Cryopreservation Strategies for the Cardiovascular System: Superiority of Vitrification over Standard slow Freezing in Murine Vessels and Efficacy of Ultrafast Rewarming by High-Intensity focused Ultrasound (HIFU) in Cardiac Recovery from Deep Hypothermia (-6ºC)
… limited, and cardiovascular grafts are highly susceptible to immune rejection. Currently, cold storage at 0–4 ºC is the gold standard for sample preservation, yet it maintains viability for only a few hours in hearts and a few days in vessels. Beyond this period, ischemic and structural …
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Advancing Transcranial Focused Ultrasound for Noninvasive Neuromodulation of Human Cortex
Ultrasound waves are mechanical undulations above the threshold for human hearing, and have been used widely in both the human body and brain for diagnostic and therapeutic purposes. Ultrasound can be controlled using specially designed transducers into a focus of a few millimeters in diameter. Low …
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Design and evaluation of a 2-D planar therapeutic ultrasound phased array
Focused ultrasound continues to be investigated as an exciting technique for several medical therapy applications including tissue ablation. Phased array transducers serve as important devices for delivering the high intensity focused ultrasound to the targeted tissue. These arrays often produce …
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Schallfeldformung zur Reduzierung der Behandlungszeit bei der Therapie mit hochenergetischen fokussierten Ultraschallwellen
… fokussierten Ultraschallwellen (HIFU, high intensity focused ultrasound) ist eine minimal invasive Methode, Tumorgewebe lokal thermisch zu zerstören. Als Ultraschallquellen werden meist hoch fokussierende Ultraschallwandler verwendet, die nur geringe Ablationsraten zulassen, was bei …
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PHOTOREFRACTIVE CRYSTAL-BASED ACOUSTO-OPTIC IMAGING IN THE NEAR-INFRARED AND ITS APPLICATIONS
… (AOI) is a dual-wave modality that combines ultrasound with diffusive light to measure and/or image the optical properties of optically diffusive media, including biological tissues such as breast and brain. The light passing through a focused ultrasound beam undergoes a phase modulation at …
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Quantitative ultrasound assessment of thermal therapy in liver
Quantitative ultrasound (QUS) is a promising technique for non-invasive tissue characterization. In this work, the potential of QUS to assess thermal therapy in liver tissue was examined. Specifically, the QUS parameters of attenuation slope, effective scatterer size (ESD), effective acoustic …
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Novel Plasmonic Nanostructures for Applications in Sensing, Imaging, and Controlled Release
… and drug delivery. The first part of this work focused on the development of novel dimeric nanostructures of Ag for surface-enhanced Raman scattering: SERS) applications. In this section, I successfully demonstrated the synthesis of well-defined Ag dimers consisting of nanospheres with a broad …
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