Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
Results
Showing 1 to 20 of 53 for “"High-cholesterol"”.
-
Plasma lipids and lipoproteins in male subjects under controlled conditions of high cholesterol feeding
… food diets, containing either 400 mg or 1400 mg cholesterol/day under controlled dietary conditions for 4 consecutive weeks. One group received a diet containing 400 mg cholesterol/day, which was contributed by non-egg food sources. The other group received a similar diet with the daily addition …
-
Effects of a high cholesterol diet on the pathogenesis of influenza A virus infection in mature mice
… elucidated. Here, we examined the effects of a high cholesterol diet in modulating the immune response to influenza A virus (IAV) infection in mice. Six-week-old C57BL/6J mice were fed either a standard rodent chow or a matched diet containing 2% cholesterol throughout the experiment. After five …
-
PKC-δ and Insulin Resistance in Non-Alcoholic Fatty Liver Disease: Effect of Vitamin D
… a link between vitamin D deficiency, high fructose diet, and NAFLD in human and rodents. The specific aim of this study is to investigate and characterize the isotype of nPKCs involved in the inhibition of IRS-1 pathway using a swine model and to evaluate the effect of vitamin D status …
-
Effects Of Cholesterol On Bovine Sperm Survival During Cooling and Freezing
… cryopreservation. One such stabilizing factor is cholesterol, which decreases the phase transition of membrane lipids that occurs during the cooling and freezing process. One known method of membrane cholesterol enrichment employs cholesterol loaded cyclodextrin (CD/CHOL). The purpose of this …
-
Use of Complementary Therapies by Individuals with or at Risk for Cardiovascular Disease and Diabetes: Results of the 2007 National Health Interview Survey
… mellitus (DM) place a heavy disease burden of high morbidity, mortality, and rising health care costs on people of the United States. With mortality reports from the two diseases of over 600,000 per year and costs in excess of $176 billion, identifying alternatives to traditional models of care …
-
Characterization and Differences Between Possible and Probable Mild Cognitive Impairment in an Alzheimer’s Disease Center
… risk factors, including APOE4, hypertension, high cholesterol, and diabetes mellitus, were examined using chi square test of independence. Demographic differences (age, education, gender, depression, and premorbid intelligence) across groups were compared using either ANOVA or chi square. …
-
Vitamin D, ADAM-12 and Carotid Artery Disease
… reduces the intimal hyperplasia in hypercholesterolemic swine, but the underlying mechanisms are not well understood. The aim of this study was to examine the effect of vitamin D on IL-6 and TNF-α-induced ADAM-12 mediated growth factor HB-EGF release, EGFR phosphorylation and SMC …
-
Dietary cholesterol in graded amounts : threshold to ceiling effects upon plasma free cholesterol synthesis, equilibration and circulation levels in humans
… study was to investigate the effect of dietary cholesterol upon plasma cholesterol concentration and cholesterogenesis; and the aspect of equilibration of newly synthesized cholesterol between plasma and red blood cell (RBC) in humans. Eight healthy subjects (seven men and one woman) at the age …
-
Afflictions of tradition: trends and consequences of traditional African American foodways
… disease, diabetes, hypertension, obesity, and high cholesterol are among the leading health concerns facing African Americans. Since these conditions are related largely to lifestyle choices, such as diet, it is important to highlight the historical social significance of African American …
-
Identification of a transducin (beta)-like 3 protein as a potential biomarker of prediabetes from rat urine using proteomics
… children. It is mainly caused by intake of diets high in fat and the lack of physical activity. Obesity is a risk factor for diseases such as type 11 diabetes, high blood pressure, high cholesterol and certain cancers. Prediabetes is a condition where blood glucose levels are above normal but have …
-
An In Vivo Characterization of the Functional Role of Two Novel Genes: StARD5 and ADAM11
<p>Regulation of cholesterol levels within cells and organisms is crucial for their survival. Maintenance of cellular cholesterol homeostasis occurs mainly at the transcriptional level, via the Sterol Regulatory Element Binding Proteins (SREBP), the Liver X Receptors (LXR), and the Unfolded Protein …
-
CHOLESTEROL INDUCED GENE EXPRESSION CHANGES IN THE BRAIN AND CEREBRAL VESSELS
Aberrant levels of cholesterol are associated with stroke and Alzheimer?s disease, but little is known regarding the effects of cholesterol on gene expression. The present study was therefore carried out using microarray-based approaches to elucidate the effects of cholesterol on gene expression …
-
Type 2 diabetes mellitus and dyslipidaemia: effects of genetic variation in African populations
… Diabetic dyslipidaemia presents as a triad of high triglycerides, high LDL and low high-density lipoprotein (HDL). Aims and Objectives: This study aimed to evaluate the role of genetic variation in genes coding for ApoE2 and PCSK9 on dyslipidaemia in South African diabetic patients. Main …
-
Sočiosios riebalų rūgštys ir jų nustatymas „Rakto skylutės“ simboliu paženklintuose maisto produktuose /
… of coronary heart diseases, strokes and a high cholesterol level in blood. The researches have shown that these diseases are associated with an elevated fat, saturated fatty acids, salt and sugar intake. In 1989, in order to prevent and reduce incidence of these diseases, authorities in …
-
Structure Determination of Natural Product Biosynthesis Enzymes
… and penicillin for the treatment of cancer, high-cholesterol-lowering and bacterial infections respectively (1–3). Total synthesis remains the primary strategy for drug and derivative production, however characterization of NP biosynthetic enzymes bears immense promise for their utility in NP …
-
ROLE OF ASGR1 IN METABOLIC SYNDROME, OBESITY, AND ATHEROSCLEROSIS
… and ASGR1 knockout (ASGR1-/-), were fed with a high-fat diet for 20 weeks (HFD). In those mice, extensive metabolic analysis and immunophenotyping were performed. Furthermore, total plasma N-glycome and untargeted liver proteomics were carried out for functional analysis. Second, to evaluate the …
-
Relationship of Anger Trait and Anger Expression to C-Reactive Protein in Post-Menopausal Women
… and risk factors, such as smoking and high cholesterol, are now well-established factors contributing to coronary heart disease pathology. A knowledge gap exists in that little is known about the mechanisms by which psychosocial factors, such as anger, may be associated with …
-
Nutrition parameters predicting functional status decline in the older adult
… status. Serum concentrations of albumin, cholesterol, hemoglobin, and percent lymphocytes and white blood cells (to calculate total lymphocyte count) were measured; fat reserves and somatic protein were estimated from anthropometry; and physical signs of malnutrition and a composite of …
-
Efavirenz pharmacogenetics and metabolic toxicity in black South Africans
… CYP2B6 slow metaboliser genotype and total cholesterol (β = 13.78, p = 0.003), LDL cholesterol (β = 15.89, p = 0.008) and HDL cholesterol (β = 24.78, p = 0.002). These associations remained significant in multivariate analyses adjusting for age, sex, weight, baseline CD4 cell count and viral …
-
Cytosolic sphingolipids and lysosome reactivation in neurodegenerative diseases
… Furthermore, it tests a bank of putative cholesterol transport inhibitors in NPCD based on reports of high cholesterol levels contributing to mitochondrial dysfunction. A chemoproteomics approach has found several proteins that bind ceramides and glycolipids. Chapter 4 sought to confirm …
Page 1 of 3