Global ETD Search
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Showing 1 to 2 of 2 for “"High-Throughput Nucleotide Sequencing"”.
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Illuminating Clonal Dynamics: Development and Use of a High-Throughput Cellular Barcoding System to Track Clonal Evolution
… and complexity. We have created an efficient and high throughput method to overcome these limitations by harnessing the power of viral marking and next generation sequencing technology, allowing us to track the clonal contributions of many thousands of cells with minimal perturbations to the …
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The Structural Distribution of Epistasis in a Pair of Essential Metabolic Enzymes
Interactions between proteins provide the basis for cells to perform metabolism, grow, divide, move, and appropriately respond to external stimuli. Because proteins do not act as independent entities, the genetic background influences the effect of a mutation in unexpected ways. This …