Global ETD Search
Search theses and dissertations gathered from participating repositories worldwide. Every result links back to the library that holds it. No account is needed.
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Showing 1 to 5 of 5 for “"High-Throughput Microscopy"”.
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Advanced image processing methods for 3D high-throughput microscopy
Advances in automated microscopy have led to the generation of vast and complex datasets, bringing bioimaging into the era of large data. This growth demands high-throughput image processing methods. This thesis addresses these challenges by developing efficient feature detection and 3D …
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CellVisualizer : exploring hierarchical, multi-dimensional data with applications to high-throughput microscopy
… system to visualize data collected by high-throughput microscopy and processed by CellProfiler, an open-source system jointly developed by researchers at MIT CSAIL and the White-head Institute. A typical high-throughput microscopy experiment produces thousands of images, with thousands …
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Quantitative analysis of proteotoxicity associated with neurodegenerative disease
… cerevisiae with microfluidics and automated microscopy. From these studies, I have found that glutamine-rich proteins suppress the toxicity of poly-glutamine expanded Huntingtin by physically interacting and sequestering the protein at the IPOD (insoluble protein deposit) quality control …
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Regulation of SRC-3 localization and dynamics by phosphorylation during ERα-dependent transcriptional activation
… (1,3,4). In the present study, using single-cell high-resolution fluorescent microscopy and high throughput microscopy (HTM) coupled to computational imaging analysis, we investigated transcriptional regulation controlled by the estrogen receptor alpha (ERalpha), in terms of large scale chromatin …
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Smart microscopy methods for quantitative microbiology
… growth, and interaction. Widefield fluorescence microscopy, in particular, has revolutionised this field by enabling high-throughput, non-invasive, time-lapse observations of cellular processes at the single-cell level. However, despite its power, this method is not without limitations. Optical …